Overview

The first section of the volume consists of four chapters giving perspectives for the current status and potential future of tissue engineering and stem cell technologies. The second section of the volume includes five chapters based on experimental and clinical data. In this section, the role of stem cells in liver tissue engineering, cell-based therapies in diabetes mellitus, and chronic degenerative diseases of the central nervous system, and adult-derived stem cell therapies are discussed. The two chapters of the third section focus on the biomarkers for tissue-engineered products, namely for tissue-engineered skin. The eight chapters of the fourth section discuss novel biomaterials developed for neural-, vascular-, aortic-, bone-, cartilage- and endocrine pancreas-tissue engineering applications. The last section of the book includes chapters on practical gene targeting applications, controlled release in gene therapy and tissue engineering, antibodies in cancer, acute-phase genes and phage-displayed peptide libraries.

Full Product Details

Author:   Y. Murat Elçin
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2003 ed.
Volume:   534
Dimensions:   Width: 17.80cm , Height: 2.20cm , Length: 25.40cm
Weight:   1.490kg
ISBN:  

9780306477881

ISBN 10:   0306477882
Pages:   340
Publication Date:   30 June 2003
Audience:   General/trade ,  Professional and scholarly ,  College/higher education ,  General ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I. Perspectives for Tissue Engineering and Stem Cells.- 1. Tissue engineering: confronting the transplantation crisis.- 2. Human embryonic stem cells-realising the potential.- 3. Human embryonic or adult stem cells: an overview on ethics and perspectives for tissue engineering.- 4. Stem cell biology and plasticity.- II. Stem Cells in Tissue Engineering and Cell - Based Therapies.- 5. Liver tissue engineering: successes and limitations.- 6. Pancreatic islet and stem cell transplantation in diabetes mellitus: results and perspectives.- 7. Cell based therapy of chronic degenerative diseases of the central nervous system.- 8. CD 34+ cells in hematopoietic stem cell transplantation.- 9. The effects of different growth factors on human bone marrow stromal cells differentiating into hepatocyte-like cells.- III. Biomarkers for Tissue-Engineered Products.- 10. Oxidative DNA damage biomarkers used in tissue-engineered skin.- 11. Biomarkers used to detect genetic damage in tissue-engineered skin.- IV. Biomaterials in Tissue Engineering and Repair.- 12. Design peptide scaffolds for regenerative medicine.- 13. Progresses in synthetic vascular prostheses: toward the endothelialization.- 14. Adhesion and growth of rat aortic smooth muscle cells on lactide-based polymers.- 15. Biodegradable copolymers carrying cell-adhesion peptide sequences.- 16. Polymer based scaffolds and carriers for bioactive agents from different natural origin materials.- 17. Preparation and characterization of natural/synthetic hybrid scaffolds.- 18. Polyhipe polymer: a novel scaffold for in vitro bone tissue engineering.- 19. Pancreatic islet culture and transplantation using chitosan and PLGA scaffolds.- V. Gene Therapy and Other Approaches.- 20. Challenges and prospects for targeted transgenesis in livestock.- 21. Controlled release of bioactive agents in gene therapy and tissue engineering.- 22. Interleukin 1 (IL-1) induces the activation of stat3.- 23. The use of antibodies in diagnosis and therapy of cancer.- 24. Detection of phage displayed peptides with blocking ability in vascular endothelial growth factor (VEGF) model.- 25. Index.

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