PARP as a Therapeutic Target

Author:   Prabal K. Chatterjee ,  Jei Zhang ,  Sandor Bernath ,  Anders Olsson (Lund University)
Publisher:   Taylor & Francis Inc
Volume:   Vol. 60
ISBN:  

9780849300738


Pages:   360
Publication Date:   06 March 2002
Format:   Hardback
Availability:   Out of stock   Availability explained


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PARP as a Therapeutic Target


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Author:   Prabal K. Chatterjee ,  Jei Zhang ,  Sandor Bernath ,  Anders Olsson (Lund University)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   Vol. 60
Dimensions:   Width: 15.60cm , Height: 2.60cm , Length: 23.40cm
Weight:   0.702kg
ISBN:  

9780849300738


ISBN 10:   0849300738
Pages:   360
Publication Date:   06 March 2002
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock   Availability explained

Table of Contents

PARP in the Nervous System. Role of PARP1 in Neurologic Disorders. The Role of PARP on Safeguarding Genomic Integrity. Functional Testing of Human PARP in Proliferation, Endotoxic Shock and Radiosensitivity. PARP Inhibitors as Neuroprotective Agents for Brain Injury. PARP-Inhibitors and Cardioprotection. Neuroprotection of the Retina with 3-Aminobenzamide, a PARP Inhibitor. PARP Inhibitors and Acute Renal Failure. Role of PARP Activation in the Pathogenesis of Shock and Inflammation. Clinical Development of the Nicotinamides and Benzamides Involving PARP as a Molecular Target. Chemoprotective Effect of a Novel PARP Inhibitor. Beneficial Effect of GPI 6150 Treatment in Multiple Animal Models of Diseases. Protective Effect of PARP Inhibition on UV Light Induced Skin Damage. Role of PARP in the Islet Injury and Vascular Complications Associated with Diabetes Mellitus. ADP-Ribose Polymer Metabolism.

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Jei Zhang

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