Overview

Biophysics deals with biological systems, such as proteins, which ful?ll a va- ety of functions in establishing living systems. While the biologistuses mostly a phenomenological description, the physicist tries to ?nd the general c- cepts to classify the materials and dynamics which underly speci?c processes. The phenomena span a wide range, from elementary processes, which can be induced by light excitation of a molecule, to communication of living s- tems. Thus, di?erent methods are appropriate to describe these phenomena. From the point of view of the physicist, this may be Continuum Mechanics to deal with membranes, Hydrodynamics to deal with transportthrough vessels, Bioinformatics to describe evolution, Electrostatics to deal with aspects of binding, Statistical Mechanics to account for temperature and to learn about the role of the entropy, and last but not least Quantum Mechanics to und- stand the electronic structure of the molecular systems involved. As can be seen from the title, Molecular Biophysics, this book will focus on systems for which su?cient information on the molecular level is available. Compared to crystallizedstandard materials studied in solid-state physics, the biological systems arecharacterizedby verybig unit cells containingproteinswith th- sands of atoms. In addition, there is always a certain amount of disorder, so that the systems can be classi?ed as complex. Surprisingly, the functions like a photocycle or the folding of a protein are highly reproducible, indicating a paradox situation in relation to the concept of maximum entropy production.

Full Product Details

Author:   Philipp O.J. Scherer ,  Sighart F. Fischer
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2010 ed.
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   0.813kg
ISBN:  

9783540856092

ISBN 10:   3540856099
Pages:   371
Publication Date:   15 July 2010
Audience:   College/higher education ,  Undergraduate ,  Postgraduate, Research & Scholarly
Replaced By:   9783662556702
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Statistical Mechanics of Biopolymers.- Random Walk Models for the Conformation.- Flory-Huggins Theory for Biopolymer Solutions.- Protein Electrostatics and Solvation.- Implicit Continuum Solvent Models.- Debye-Huckel Theory.- Protonation Equilibria.- Reaction Kinetics.- Formal Kinetics.- Kinetic Theory: Fokker-Planck Equation.- Kramers' Theory.- Dispersive Kinetics.- Transport Processes.- Nonequilibrium Thermodynamics.- Simple Transport Processes.- Ion Transport Through a Membrane.- Reaction-Diffusion Systems.- Reaction Rate Theory.- Equilibrium Reactions.- Calculation of Reaction Rates.- Marcus Theory of Electron Transfer.- Elementry Photophysis.- Molecular States.- Optical Transitions.- The Displaced Harmonic Oscillator Model.- Spectral Diffusion.- Crossing of Two Electronic States.- Dynamics of an Excited State.- Elementry Photoinduced Processes.- Photophysics of Chlorophylls and Carotenoids.- Incoherent Energy Transfer.- Coherent Excitations in Photosynthetic Systems.- Ultrafast Electron Transfer Processes in the Photosynthetic Reaction Center.- Proton Transfer in Biomolecules.- Molecular Motor Models.- Continuous Ratchet Models.- Discrete Ratchet Models.- The Grand Canonical Ensemble.- Time Correlation Function of the Displaced Harmonic Oscillator Model.- The Saddle Point Method.

Reviews

From the reviews: Intended for graduate students, Theoretical Molecular Biophysics by Philipp Scherer and Sighart Fischer grew out of a biophysics course taught by the authors in the physics department of the Technical University of Munich. ! A striking feature of Theoretical Molecular Biophysics is the large number of equations relative to text ! . chapters close with challenging problems whose solutions are provided at the end of the book. ! The book closes with an interesting review of molecular-motor models. (H. Richard Leuchtag, Physics Today, May, 2011)

From the reviews: Intended for graduate students, Theoretical Molecular Biophysics by Philipp Scherer and Sighart Fischer grew out of a biophysics course taught by the authors in the physics department of the Technical University of Munich. ... A striking feature of Theoretical Molecular Biophysics is the large number of equations relative to text ... . chapters close with challenging problems whose solutions are provided at the end of the book. ... The book closes with an interesting review of molecular-motor models. (H. Richard Leuchtag, Physics Today, May, 2011)

Author Information

P.Scherer: 1984 PhD in experimental and theoretical physics 1996 Habilitation in theoretical physics 2001 and 2003, visiting scientist at AIST, Tsukuba, Japan since 1999 lecturer at Technische Universitat Munchen 2006-2008 temporary leader of the institute for theoretical biomolecular physics T38 at TUM S.Fischer: 1965 PhD in theoretical physics in Gottingen with Professor F. Hund 1966-1969 Postdoctoral Fellow and Instructor at Northwestern University and at the University of Chicago 1970-1974 Professor at the Nortwestern University, Evanston Since 1974 Universitatsprofessor fur Theoretische Physik ,T38 Technische Universitat Munchen since 2006 emeritus

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