Overview

Vitamin D (Vit D) Mangel ist häufig bei Dialysepatienten zu beobachten. Previous studies suggest that 50 to 90% of end stage renal disease (ESRD) patients are deficiency in vit D. In Tunisia, studies regarding hypovitaminosis D in patients on dialysis are not numerous. Actually, many data support the use of native vit D in hemodialysis patients. In Tunisia, using native vit D is not part of therapeutic habits of all dialysis centers.The aim of this study is to determine the prevalence of vit D deficiency in patients with CKD stage 5 undergoing hemodialysis (HD) and to evaluate the effect of oral Cholecalciferol supplementation, in intact parathormon hormon (iPTH), serum calcium (Ca) and serum phosphorus (ph). We conducted a pre-experimental study among HD patients. Monthly Oral supplementation with Cholecalciferol, was instituted for six months.Fourty three participants were included. Die durchschnittliche Konzentration von 25 Hydroxy-Vitamin D (25(OH) D) betrug 17,89 ng/ml. Vit D deficiency was observed in 83.7% of our patients. Wir beobachteten einen signifikanten Anstieg der 25OH-Vitamin-D- und Ca-Spiegel und einen signifikanten Rückgang der iPTH-Spiegel. Keine offensichtliche Toxizität, keine schwere Hypercalcemie oder Hyperphosphat.

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