Overview

The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a mass of molecules. The book provides updated applications of MALDI-TOF techniques in clinical microbiology, presenting the latest information available on a technology that is now used for rapid microbial identification at relatively low cost, thus offering an alternative to conventional laboratory diagnosis and proteomic identification systems. Although the main use of the technology has, until now, been identification or typing of bacteria from a positive culture, applications in the field of virology, mycology, microbacteriology and resistances are opening up new opportunities.

Full Product Details

Author:   Fernando Cobo (Hospital de Poniente, Spain)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.480kg
ISBN:  

9780128144510

ISBN 10:   0128144513
Pages:   298
Publication Date:   09 August 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Proteomics: technology and applications 2. Basis on mass spectrometry. Technical variants 3. MALDI-TOF commercial platforms for microbial identification 4. Work procedures in MALDI-TOF technology 5. Indications, interpretation of results, advantages, disadvantages and limitations of MALDI-TOF 6. Quality control in MALDI-TOF techniques 7. Application of MALDI-TOF for bacterial identification 8. Detection of bacterial resistance through MALDI-TOF technology 9. Direct identification of pathogens from positive blood cultures by MALDI-TOF technology 10. Use of MALDI-TOF techniques in the diagnosis of urinary tract pathogens 11. Direct application of MALDI-TOF mass spectrometry to cerebrospinal fluid for pathogen identification 12. Application of MALDI-TOF in clinical virology 13. Use of MALDI-TOF mass spectrometry in microbacterial diagnosis 14. Use of MALDI-TOF mass spectrometry in fungal diagnosis 15. Application of MALDI-TOF in bacterial strain typing and taxonomy 16. Future applications of MALDI-TOF mass spectrometry in clinical microbiology

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Author Information

Dr Fernando Cobo is a specialist in microbiology working in the Microbiology Department of the Hospital de Poniente, Spain, and has previously worked at the University Hospital Virgen de las Nievas and the Stem Cell Bank of Andalucía. He is a member of several professional societies including the Spanish Society of Infectious Diseases and Clinical Microbiology, and has published over 50 peer-reviewed journal articles, 10 books, 90 book chapters, and 120 national and international conference papers.

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