Overview
A guide to making optimal use of one of the most important tools available to today's synthetic organic chemist Compatible with virtually all functional groups without protection and capable of forming carbon-carbon bonds under neutral conditions-often with complete stereospecificity-the Stille reaction is an indispensable component of the synthetic organic chemist's toolkit. In the years since Stille's pioneering work, chemists have developed a vast number of applications for this incredibly versatile metal-catalyzed cross-coupling reaction. This paperback edition of the 50th volume in the definitive Organic Reactions series describes many of those uses. Drawing upon their considerable experience as professional synthetic organic chemists who have worked extensively with the Stille reaction, the authors approach their subject from the preparative viewpoint, paying particular attention throughout to limitations, interfering influences, effects of structure, and the selection of experimental techniques. Focusing primarily on the single reaction of the Stille reaction, they provide comprehensive coverage of: * Experimental conditions and selecting optimal experimental parameters * Traditional and recently developed experimental procedures * Side reactions and techniques for avoiding them * Documented reactions-33 tables list 570 reactions, complete withconditions, yields, structures of major products, and common failures * Easy-to-follow recipes for casual users of the Stille reaction The Stille Reaction is an indispensable working resource for all synthetic organic chemists, especially medicinal chemists. It is also an excellent graduate-level text for students of organic and medicinal chemistry.
Full Product Details
Author: Vittorio Farina (Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut) ,
Venkat Krishnamurthy (Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut) ,
William J. Scott (Institute of Chemistry, Bayer Corporation, West Haven, Connecticut)
Publisher: John Wiley & Sons Inc
Imprint: John Wiley & Sons Inc
Dimensions:
Width: 15.40cm
, Height: 3.30cm
, Length: 22.80cm
Weight: 0.907kg
ISBN: 9780471312734
ISBN 10: 0471312738
Pages: 672
Publication Date: 12 October 1998
Audience:
College/higher education
,
Professional and scholarly
,
Postgraduate, Research & Scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Out of stock
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Author Information
VITTORIO FARINA, PhD, is Director at the Boehringer Ingelheim Pharmaceuticals Department of Chemical Development. VENKAT KRISHNAMURTHY, PhD, is a research chemist with Occidental Chemical Corporation. WILLIAM J. SCOTT is a research chemist with the Bayer Corporation Institute of Chemistry, Department of Medicinal Chemistry.
