The Role of Pendrin in Health and Disease: Molecular and Functional Aspects of the SLC26A4 Anion Exchanger

Author:   Silvia Dossena ,  Markus Paulmichl
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2017
ISBN:  

9783319432854


Pages:   226
Publication Date:   10 March 2017
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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The Role of Pendrin in Health and Disease: Molecular and Functional Aspects of the SLC26A4 Anion Exchanger


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Author:   Silvia Dossena ,  Markus Paulmichl
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2017
Weight:   4.784kg
ISBN:  

9783319432854


ISBN 10:   3319432850
Pages:   226
Publication Date:   10 March 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Pendrin and the Pendrin Consortium.- Pendrin role in the inner ear.- Pendrin role in the thyroid and Pendred syndrome.- Pendrin role in the kidney and hypertension.- Interplay between Pendrin and other renal transport molecules.- Pendrin role in the airways: links with asthma and COPD.- Pendrin expression and function in non-conventional sites.- Transcriptional regulation and epigenetics of Pendrin.- Models for Pendrin structure.- Genetic diagnosis of deafness.- Functional and molecular properties of Pendrin allelic variants.- Potential pharmacological interventions for Pendrin dysfunction.

Reviews

The purpose is to summarize the current knowledge about the role of pendrin in normal physiology and disease pathology. The intended audience is predominantly researchers and physicians interested in a detailed description of the multifaceted function of pendrin. However, the book also could serve as a good source for undergraduate and graduate students and postgraduate trainees interested in thyroid physiology and pathology as well as physiology, pathology, and diagnosis of deafness in general. (Partha Kasturi, Doody's Book Reviews, June, 2017)


Author Information

Prof. Dr. Markus Paulmichl Institute of Pharmacology and Toxicology of the Paracelsus Medical University Salzburg, Austria Silvia Dossena, PhD Institute of Pharmacology and Toxicology of the Paracelsus Medical University Salzburg, Austria

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