Overview

Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter like role in vascular endothelium, a scond-messenger role in N-methyl-D-aspartate (NMDA) responsive neurons in the central nervous system (CNS), a neurotoxic role after its release from these neurons, and a cytotoxic role after its release by macrophages. This volume reviews among other topics the basic chemistry and physical properties of S-nitrosothiols (RS-NO) and their biochemical mechanisms of action, NO synthase isozymes, NO synthase structure, mechanisms of NO synthesis, regulation of NOS expression and posttranslational modification, and mechanisms involving NO of CNS's damage in virus infections.

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9783642791321

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"""In the past six years, the field of nitric oxide research has undergone explosive growth.... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction ...."" Journal of Chemical Neuroanatomy"

In the past six years, the field of nitric oxide research has undergone explosive growth.... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction .... Journal of Chemical Neuroanatomy

In the past six years, the field of nitric oxide research has undergone explosive growth... This volume can be taken as a short introduction to the field of nitric oxide research. For the advanced student or the scientist who wants a quick impression of major aspects of this field it may be a good introduction ... Journal of Chemical Neuroanatomy

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