The Role of MHC and Non-MHC Antigens in Allograft Immunity

Author:   T. Mohanankumar
Publisher:   Taylor & Francis Inc
ISBN:  

9781879702875


Pages:   114
Publication Date:   01 January 1994
Format:   Hardback
Availability:   In Print   Availability explained
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The Role of MHC and Non-MHC Antigens in Allograft Immunity


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Overview

Minor histocompatability antigens (MHA) are a group of cell-surface membrane proteins that are able to exclusively mediate a cellular immune response. These antigens (Ag) were initially distinguished from major histocompatibility antigens (MHC) by their weak immunogenicity in allograft transplants. As information describing their structure and function accumulated, the term MHA was misleading because these immunogens were neither weak nor minor. It became clear that non-MHC histocompatible antigens (non-MHC-HA) was a more appropriate name. Non-MHC HA are involved not only in transplantation but also in defining immunologic self and shaping the T cell reprtoire. This book investigates the biology of the non-MHC HA and their role in clinical medicine.

Full Product Details

Author:   T. Mohanankumar
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Weight:   0.560kg
ISBN:  

9781879702875


ISBN 10:   1879702878
Pages:   114
Publication Date:   01 January 1994
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Biology of Major Histocompatibility Complex. MHC and the Allograft Immune Response. NonMHC Antigens in Allograft Immunity.

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