Overview

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines-all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book's multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Full Product Details

Author:   Shaker A. Mousa ,  Raj Bawa ,  Gerald F. Audette
Publisher:   Pan Stanford Publishing Pte Ltd
Imprint:   Pan Stanford Publishing Pte Ltd
Weight:   2.286kg
ISBN:  

9789814800594

ISBN 10:   9814800597
Pages:   1208
Publication Date:   12 February 2020
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Mixed media product
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Drug Delivery at the Nanoscale: A Guide for Scientists, Physicians and Lawyers. What Is Precision Medicine? A Primer on Contemporary Issues and Concerns. FDA's Role in Paving the Way for Personalized Medicine. Multifunctional Gold Nanoparticles in Drug Delivery Systems. Nanoparticles and Nanoparticulate Drug Delivery Systems: Impact of Size and Structure on Functionality. Self-Assembling Peptide Amphiphiles as a Versatile Future Nanomedicine Platform. Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery. Nanomaterials: Tools, Technology, and Methodology of Nanotechnology-Based Biomedical Systems for Diagnostics and Therapy. Nanomagnetic Resonance Imaging (Nano-MRI) Gives Personalized Medicine a New Perspective. Advancing Precision Medicine: Tailoring Personalized Therapies. Precision Medicine for Alzheimer's Disease Prevention. Advanced Porphyrin Nanomaterials for Biological Applications. Cerium Oxide Nanoparticles as a Novel Reactive Oxygen Modulating Nanodrug. Artificial Nanomachines and Nanorobotics. Nanomotors for Nucleic Acid, Protein, Pollutant, and Cell Detection. Magneto-Responsive Scaffolds for Tissue Engineering Applications. Anti-Cancer and Anti-Angiogenic Properties of Nano-Diamino-Tetrac, A Thyroid Hormone Derivative. Proteomic Profiling and Predictive Biomarkers in Neuro-Traumatology and Neuro-Oncology. Nanomedicine and Personalized Care: Facts and Fiction. Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer. Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment. Views from the FDA: Precision Medicine, Genetic Variant Databases and Companion Diagnostics. Protein-Based Nanoparticle Materials for Medical Applications. Nanomedicine and Phage Capsids. Pharmacogenomics: Ethical, Social, and Public Policy Issues. From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology. Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs. Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine. Precision or Personalized Medicine for Cancer Chemotherapy: Is There a Role for Herbal Medicine?. Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine. Stem Cell Banking for Regenerative and Personalized Medicine. Overview of Ethical Issues in Nanomedicine. Amphiphilic Nanocarrier Systems for Curcumin Delivery in Neurodegenerative Disorders. Peptide-Based Drug Delivery Systems: Future Challenges, Perspectives, and Opportunities in Nanomedicine. Hydrogels and Their Applications in Targeted Drug Delivery. Emergence of Real World Evidence in Precision Medicine.

Reviews

The carefully-selected range of topics in this masterpiece will be equally beneficial to academia, physicians, drug industry, business, healthcare systems, policymakers, geneticists, regulatory bodies and governments. In the coming decade efforts in nanomedicine and precision medicine will be translated from the bench to the bedside, paving the way for more accurate diagnosis and more precise therapeutics. This review volume is a standard reference resource for anyone involved in the coming healthcare revolution. Tatiana K. Bronich, University of Nebraska Medical Center, USA The first 3 volumes in this series have been inspirational and form the most definitive and useful references for anyone wishing to know about the technical, clinical, legal, business and regulatory aspects of nanomedicine. The topic has in the past raised expectations to levels that were probably too high, but anyone reading these books will understand the opportunities and barriers much better. This fourth volume was awaited with great interest. Peter J. Dobson, University of Oxford, UK It is wonderful to see that Nobel Laureate Paul Ehrlich's vision of magic bullets postulated in 1908 may eventually be fully realized along the road from nanomedicine to precision medicine. The power unleashed by elucidation of the genome coupled with the elegance of site-specific drug delivery will revolutionize healthcare in the next century. In my 70-years as a researcher and university professor, nothing has held a greater potential to diagnose and treat diseases in a more customizable, targeted manner. This masterful volume reflects the innovative developments, potential applications and possible bottle-necks in these two interrelated fields. S. R. Bawa, Panjab University, India Precision medicine and targeted nanomedicines are the Holy Grail of medicine and drug delivery; this comprehensive volume highlights their salient features and interconnectivity. A team of distinguished editors and authors have done a superb job focussing on the critical and current issues, masterfully dissecting hype from reality. Janos Szebeni, Semmelweis University School of Medicine, Budapest, Hungary The growth, opportunity and promise of nanomedicine has become breathtaking which is why The Road from Nanomedicine to Precision Medicine by Mousa, Bawa and Audette is my go to reference. It puts cutting-edge nano-developments in context of personalized/precision medicine and the lessons learned from applications in one clinical challenge may serve as a template for other challenges. Use this volume as a reference but be sure to read it for inspiration. Nicholas Borys, Celsion Corporation, New Jersey, USA As nanomedicine begins to mature further and evolves towards enabling precision medicine, this volume with its punctiliously selected content is destined to become a must-have reference resource. The editors have made an astounding effort that connects different manifestations of nanomedicines with the many modes of developing precision medicine, while illuminating the regulatory pathway and challenges therein for all of us to learn from. Its unique contents will be especially useful to oncology, infectious diseases, degenerative diseases and regenerative medicine. Anil R. Diwan, PhD, NanoViricides, Inc., Connecticut, USA The untapped solutions from nanotechnology will enable breakthroughs in customized healthcare. This comprehensive edition provides the groundwork of where nanomedicine will lead to tailoring precision medicine for individual patient care. Neil Gordon, Guanine Inc., New York, USA

The carefully-selected range of topics in this masterpiece will be equally beneficial to academia, physicians, drug industry, business, healthcare systems, policymakers, geneticists, regulatory bodies and governments. In the coming decade efforts in nanomedicine and precision medicine will be translated from the bench to the bedside, paving the way for more accurate diagnosis and more precise therapeutics. This review volume is a standard reference resource for anyone involved in the coming healthcare revolution. Tatiana K. Bronich, University of Nebraska Medical Center, USA The first 3 volumes in this series have been inspirational and form the most definitive and useful references for anyone wishing to know about the technical, clinical, legal, business and regulatory aspects of nanomedicine. The topic has in the past raised expectations to levels that were probably too high, but anyone reading these books will understand the opportunities and barriers much better. This fourth volume was awaited with great interest. Peter J. Dobson, University of Oxford, UK It is wonderful to see that Nobel Laureate Paul Ehrlich's vision of magic bullets postulated in 1908 may eventually be fully realized along the road from nanomedicine to precision medicine. The power unleashed by elucidation of the genome coupled with the elegance of site-specific drug delivery will revolutionize healthcare in the next century. In my 70-years as a researcher and university professor, nothing has held a greater potential to diagnose and treat diseases in a more customizable, targeted manner. This masterful volume reflects the innovative developments, potential applications and possible bottle-necks in these two interrelated fields. S. R. Bawa, Panjab University, India Precision medicine and targeted nanomedicines are the Holy Grail of medicine and drug delivery; this comprehensive volume highlights their salient features and interconnectivity. A team of distinguished editors and authors have done a superb job focussing on the critical and current issues, masterfully dissecting hype from reality. Janos Szebeni, Semmelweis University School of Medicine, Budapest, Hungary The growth, opportunity and promise of nanomedicine has become breathtaking which is why The Road from Nanomedicine to Precision Medicine by Mousa, Bawa and Audette is my go to reference. It puts cutting-edge nano-developments in context of personalized/precision medicine and the lessons learned from applications in one clinical challenge may serve as a template for other challenges. Use this volume as a reference but be sure to read it for inspiration. Nicholas Borys, Celsion Corporation, New Jersey, USA As nanomedicine begins to mature further and evolves towards enabling precision medicine, this volume with its punctiliously selected content is destined to become a must-have reference resource. The editors have made an astounding effort that connects different manifestations of nanomedicines with the many modes of developing precision medicine, while illuminating the regulatory pathway and challenges therein for all of us to learn from. Its unique contents will be especially useful to oncology, infectious diseases, degenerative diseases and regenerative medicine. Anil R. Diwan, PhD, NanoViricides, Inc., Connecticut, USA The untapped solutions from nanotechnology will enable breakthroughs in customized healthcare. This comprehensive edition provides the groundwork of where nanomedicine will lead to tailoring precision medicine for individual patient care. Neil Gordon, Guanine Inc., New York, USA

Author Information

Shaker A. Mousa, PhD is an endowed chair, tenured professor of Pharmacology at Albany College of Pharmacy; Vice Provost of Research, executive vice president, and chair of Pharmaceutical Research Institute at Albany, NY. Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, VA, USA that he founded in 2002. Gerald F. Audette, PhD, is an Associate Professor in the Department of Chemistry and member of the Centre for Research on Biomolecular Interactions at York University in Toronto, Canada.

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