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Author:   Shlomo Melmed (Professor of Medicine, Dean of the Medical Faculty, Cedars Sinai Health System, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   3rd edition
Dimensions:   Width: 21.60cm , Height: 3.80cm , Length: 27.60cm
Weight:   2.360kg
ISBN:  

9780123809261

ISBN 10:   0123809266
Pages:   744
Publication Date:   09 December 2010
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Replaced By:   9780128041697
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Section 1 Hypothalamic-Pituitary Function 1. Functional Anatomy of the Hypothalamic Pituitary Axis Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles 2. Adrenocorticotropin Mark A. Herman, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas Joseph A. Majzoub, Children’s Hospital, Harvard Medical School, Division of Endocrinology, Boston 3. Growth Hormone Vivien S. Herman-Bonert, UCLA School of Medicine, Division of Endocrinology, Los Angeles Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles 4. Prolactin Mark E. Molitch, Northwestern University Medical School, Center for Endocrinology, Metabolism, and Molecular Medicine 5. Thyroid-stimulating Hormone Chester E. Ridgway, University of Colorado Health Sciences Center, Division of Endocrinology 6. Follicle-stimulating Hormone and Leutinizing Hormone Ronald S. Swerdloff, Harbor/UCLA Medical Center, UCLA School of Medicine, Division of Endocrinology Shalender Bhasin, Drew University School of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine 7. The Posterior Pituitary Daniel G. Bichet, University of Montreal, Department of Medicine, Montreal Section 2 Hypothalamic-Pituitary Dysfunction 8. The Hypothalamus Glenn D. Braunstein, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles 9. Anterior Pituitary Failure Charles F. Abboud, Mayo Clinic, Mayo Medical School, Rochester Sect. 3 Pituitary Tumors 10. Pituitary Surgery Rudolf Fahlbusch, Professor of Neurosurgery, University of Erlangen-Nurnberg, Germany 11. Radiation and Non-surgical Management of the Pituitary Laurence Katznelson, Stanford University School of Medicine, Department of Neurosurgery, Stanford 12. Acromegaly Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles 13. Prolactinoma Mark E. Molitch, Northwestern University Medical School, Center for Endocrinology, Metabolism, and Molecular Medicine 14. Cushing's Disease Lynn Loriaux , Oregon Health & Science University, Chair, Department of Medicine, Portland Jean–Pierre Luton, Professor of Endocrinology, Cochin Medical School, University Rene Decartes, Paris, France 15. Thyrotropin-secreting Pituitary Tumors Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles 16. Gonadotroph Adenomas Margaret E. Wierman, University of Colorado Health Sciences Center, Division of Endocrinology, Denver Peter J. Snyder, University of Pennsylvania School of Medicine, Philadelphia 17. Other Piuitary Lesions Stephen A. Geller, UCLA, School of Medicine, Los Angeles Section 4 Pituitary Disease in Systemic Disorders 18. Pituitary Function in Systemic Disorders William F. Chandler, University of Michigan, Pituitary and Neuroendocrine Center, Ann Arbor 19. The Pituitary Gland in Pregnancy and the Puerperium Errol R. Norwitz, Yale University School of Medicine, Division of Maternal-Fetal Medicine, New Haven 20. Drugs and Pituitary Function Elizabeth Ginsberg, Brigham and Women’s Hospital, Harvard University Medical School Section 5 Diagnostic Procedures 21. Pituitary Imaging Barry D. Pressman, Cedars-Sinai Medical Center, Chief, Section of Neuroradiology and Chairman, Department of Imaging, Los Angeles 22. Neuro-ophthalmologic Evaluation of Pituitary Disorders Anthony C. Arnold, UCLA, Department of Opthalmology, Los Angeles 23. Evaluation of Normal Pituitary Function Gillian L. Booth, Department of Medicine, University of Toronto, Canada

Reviews

SECOND EDITION: This excellent second edition is an update of the highly successful first edition of The Pituitary, published in 1995.All the chapters were written by leading experts in the field; a particularly welcome addition is a chapter dedicated to pituitary surgery, by Fahlbusch and colleagues. All the chapters have been successfully updated, and all are comprehensively referenced. The new edition describes recent developments in medical therapies for acromegaly (and thyrotropin-producing adenomas), especially the role of long-acting forms of somatostatin analogues and new growth hormone-receptor antagonists, as well as newer and more effective dopamine agonists for patients with prolactinoma. Inevitably, availability and licensing are subject to worldwide variations and differences in therapeutic practice. Not all the chapters recognize the differences between the United States and other parts of the world, especially Europe, in the availability of therapies that can be offered to patients with pituitary disease. The chapter on hypopituitarism does not fully address the various ways we can now deliver androgen replacement (and their pros and cons) and still mentions the use of extracts of animal thyroids in managing thyrotropin deficiency. There is an extensive discussion of growth hormone deficiency and its treatment with recombinant human growth hormone, but the sensitive and clinically critical issue of whether this expensive therapy should be prescribed for all adults with growth hormone deficiency or only for selected subgroups is avoided. These minor points should not detract from the view that this is a truly excellent book. It is clearly written, and nearly all of it is easy to read. I believe it is an essential and important textbook for practicing endocrinologists and endocrine scientists, trainees in endocrinology, and those working with endocrinologists in the care of patients with pituitary disease, including pediatricians, surgeons, radiologists, oncologists, and endocrine biochemists. It is a fitting tribute, indeed, to the gland that represents the conductor of the endocrine orchestra. -- The New England Journal of Medicine FIRST EDITION: I strongly recommend this book. It fills a void in literature by providing in-depth coverage of the pituitary. The book will serve endocrinologists as a source of information on the various aspects of pituitary disease, blending clinical and basic science into a cohesive and comprehensive story. -- New England Journal of Medicine, December 1995 The depth of treatment is impressive throughout and all chapters are highly readable.this book is well worth its price. -- Journal of Neurosurgery, January 1996

""".the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ""master gland"" by one of the most important opinion leaders in the field.""--Endocrine 2012 vol.41 p.159 ""[T]he book provides the reader a unique opportunity to understand in depth the mechanisms subserving both normal and disordered pituitary hormone secretion and action. Thus, the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ""master gland"" by one of the most important opinion leaders in the field.""--Endocrine SECOND EDITION: ""This excellent second edition is an update of the highly successful first edition of The Pituitary, published in 1995.All the chapters were written by leading experts in the field; a particularly welcome addition is a chapter dedicated to pituitary surgery, by Fahlbusch and colleagues. All the chapters have been successfully updated, and all are comprehensively referenced. The new edition describes recent developments in medical therapies for acromegaly (and thyrotropin-producing adenomas), especially the role of long-acting forms of somatostatin analogues and new growth hormone-receptor antagonists, as well as newer and more effective dopamine agonists for patients with prolactinoma. Inevitably, availability and licensing are subject to worldwide variations and differences in therapeutic practice. Not all the chapters recognize the differences between the United States and other parts of the world, especially Europe, in the availability of therapies that can be offered to patients with pituitary disease. The chapter on hypopituitarism does not fully address the various ways we can now deliver androgen replacement (and their pros and cons) and still mentions the use of extracts of animal thyroids in managing thyrotropin deficiency. There is an extensive discussion of growth hormone deficiency and its treatment with recombinant human growth hormone, but the sensitive and clinically critical issue of whether this expensive therapy should be prescribed for all adults with growth hormone deficiency or only for selected subgroups is avoided. These minor points should not detract from the view that this is a truly excellent book. It is clearly written, and nearly all of it is easy to read. I believe it is an essential and important textbook for practicing endocrinologists and endocrine scientists, trainees in endocrinology, and those working with endocrinologists in the care of patients with pituitary disease, including pediatricians, surgeons, radiologists, oncologists, and endocrine biochemists. It is a fitting tribute, indeed, to the gland that represents the ""conductor of the endocrine orchestra.""--The New England Journal of Medicine FIRST EDITION: ""I strongly recommend this book. It fills a void in literature by providing in-depth coverage of the pituitary. The book will serve endocrinologists as a source of information on the various aspects of pituitary disease, blending clinical and basic science into a cohesive and comprehensive story.""-- New England Journal of Medicine, December 1995 ""The depth of treatment is impressive throughout and all chapters are highly readable.this book is well worth its price.""-- Journal of Neurosurgery, January 1996"

[T]he book provides the reader a unique opportunity to understand in depth the mechanisms subserving both normal and disordered pituitary hormone secretion and action. Thus, the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the master gland by one of the most important opinion leaders in the field. --Endocrine SECOND EDITION: This excellent second edition is an update of the highly successful first edition of The Pituitary, published in 1995.All the chapters were written by leading experts in the field; a particularly welcome addition is a chapter dedicated to pituitary surgery, by Fahlbusch and colleagues. All the chapters have been successfully updated, and all are comprehensively referenced. The new edition describes recent developments in medical therapies for acromegaly (and thyrotropin-producing adenomas), especially the role of long-acting forms of somatostatin analogues and new growth hormone-receptor antagonists, as well as newer and more effective dopamine agonists for patients with prolactinoma. Inevitably, availability and licensing are subject to worldwide variations and differences in therapeutic practice. Not all the chapters recognize the differences between the United States and other parts of the world, especially Europe, in the availability of therapies that can be offered to patients with pituitary disease. The chapter on hypopituitarism does not fully address the various ways we can now deliver androgen replacement (and their pros and cons) and still mentions the use of extracts of animal thyroids in managing thyrotropin deficiency. There is an extensive discussion of growth hormone deficiency and its treatment with recombinant human growth hormone, but the sensitive and clinically critical issue of whether this expensive therapy should be prescribed for all adults with growth hormone deficiency or only for selected subgroups is avoided. These minor points should not detract from the view that this is a truly excellent book. It is clearly written, and nearly all of it is easy to read. I believe it is an essential and important textbook for practicing endocrinologists and endocrine scientists, trainees in endocrinology, and those working with endocrinologists in the care of patients with pituitary disease, including pediatricians, surgeons, radiologists, oncologists, and endocrine biochemists. It is a fitting tribute, indeed, to the gland that represents the conductor of the endocrine orchestra. -- The New England Journal of Medicine FIRST EDITION: I strongly recommend this book. It fills a void in literature by providing in-depth coverage of the pituitary. The book will serve endocrinologists as a source of information on the various aspects of pituitary disease, blending clinical and basic science into a cohesive and comprehensive story. -- New England Journal of Medicine, December 1995 The depth of treatment is impressive throughout and all chapters are highly readable.this book is well worth its price. -- Journal of Neurosurgery, January 1996

Author Information

Shlomo Melmed, MB, ChB, FRCP, MACP, is Executive VP and Dean of the Medical Faculty at Cedars-Sinai Medical Center. He leads Cedars-Sinai’s research and education programs, recruiting nationally recognized faculty leadership, establishing new educational programs and maintaining the highest academic standards. Dr. Melmed holds the Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine. An international authority on pituitary medicine, he has pioneered the discovery and application of novel treatments for endocrine tumors and has authored more than 350 peer-reviewed articles. Dr. Melmed has been a faculty leader at Cedars-Sinai for nearly 40 years and has been the health system’s chief academic officer since 1998. Dr. Melmed's laboratory consistently has received competitive grant awards from the National Institutes of Health since 1980, and he has trained over 80 physicians, scientists and graduate students who occupy leading positions in academic endocrinology worldwide. He is on the editorial board of the Journal of Clinical Investigation and is also an Associate Dean of the UCLA School of Medicine.

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