The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence
Author:   Monica E. Embers
Publisher:   Springer-Verlag New York Inc.
Edition:   2012 ed.
ISBN:  

9781461454038


Pages:   268
Publication Date:   07 December 2012
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence


Overview

​This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host.  Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites.  We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.

Full Product Details

Author:   Monica E. Embers
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2012 ed.
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.595kg
ISBN:  

9781461454038


ISBN 10:   1461454034
Pages:   268
Publication Date:   07 December 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

​Treponema pallidum.- Immunoseclusion and Chronic Infection.- Treponema Denticola.- Borrelial Complement-binding Proteins.- Treponema Pallidum Repeat (tpr) Genes and Antigenic Variation.- Antigenic Variation of V1sE by Borrelia Burgdorferi.- Modulation of Cytokine Signaling by Borrelia Burgdorferi.- Leptospira: Invasion, Pathogenesis and Persistence.- Immune Resistance by Relapsing  Fever Spirochetes.- Neuroborreliosis Caused by Borrelia Burgdorferi: Possible Role of Glial Cells.- Antibiotic Resistance in Treponema Pallidum subsp. Pallidum, the Syphilis Agent.- Borrelia Burgdorferi Persistence Post-Antibiotic Treatment.

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