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Author:   Iain J. McEwan, PhD
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 2nd ed. 2016
Volume:   1443
Dimensions:   Width: 17.80cm , Height: 1.40cm , Length: 25.40cm
Weight:   4.946kg
ISBN:  

9781493981205

ISBN 10:   149398120
Pages:   250
Publication Date:   26 May 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The Nuclear Receptor Superfamily- At Thirty.- Lipid Homeostasis and Ligands for Liver X Receptors: Identification and Characterization.- Use of Differential Scanning Fluorimetry to Identify Nuclear Receptor Ligands.- Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor.- Use of BRET to Study Protein-Protein Interactions in vitro and in vivo.- Studying Steroid Receptor Complexes in the Cellular Environment.- Post-translational Modifications of Steroid Receptors: Phosphorylation.- Mapping protein-DNA Interactions using ChIP-exo and Illumina-based Sequencing.- Methods to Identify Chromatin Bound Protein Complexes: From Genome-Wide to Locus Specific Approaches.- Measuring the Expression of microRNAs Regulated by Androgens.- Methods for Identifying and Quantifying Mrna Expression of Androgen Receptor Splicing Variants in Prostate Cancer.- Harvesting Human Prostate Tissue Material and Culturing Primary Prostate Epithelial Cells.- In vivo Imaging of Nuclear Receptor Transcriptional Activity.- Development and Characterisation of Cell-Specific Androgen Receptor Knockout Mice.

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