Overview

The most useful reactions of organonitro compounds in organic synthesis Compounds containing nitro groups are useful intermediates for the synthesis of natural products and other complex organic molecules. The Nitro Group in Organic Synthesis focuses on reactions that proceed under mild conditions, important functional groups that can be synthesized by conversion of nitro groups, and the stereoselectivity of reactions of nitro compounds. These issues are of great importance to practicing researchers in today's pharmaceutical, agrochemical, and fine chemical industries. The Nitro Group in Organic Synthesis also emphasizes environmentally-friendly methods for nitration, the importance of aliphatic nitro compounds, and modern preparation of nitro compounds. Other topics discussed include: * Henry reaction * Asymmetric Michael addition * Alkylation, acylation, halogenation, and related reactions of RNO2 * Substitution and elimination of NO2 and RNO2 The Nitro Group in Organic Synthesis is a useful resource for researchers and students in organic and medicinal chemistry.

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9780471316114

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Reviews

Special attention is paid to environmentally--friendly methods for nitration, and new reactions discovered in recent years. (SciTech Book News, Vol. 25, No. 3, September 2001) This book is a very useful reference work that is highly recommended to synthetic organic chemists who might use nitro compounds in their work. (Polymer News, Vol. 26, No. 9, 2001) ...a valuable addition to institutional libraries and to the personal library of scientists... Highly recommended. (Journal of Medicinal Chemistry, Vol. 45, No. 6, 2002) excellent coverage of the use of nitro groups in organic synthesis (Chemistry & Industry, 15 April 2002)

Author Information

NOBORU ONO is Professor of Organic Chemistry in the Department of Chemistry at Ehime University, Matsuyama, Japan.

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