The Molecular and Ionic Signalling of Neutrophils

Author:   M.B. Hallett (University of Wales College of Medicine, Cardiff) ,  D. Lloyds (University of Cardiff)
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:  

9783540631262


Pages:   180
Publication Date:   01 September 1997
Format:   Hardback
Availability:   Out of stock   Availability explained
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The Molecular and Ionic Signalling of Neutrophils


Overview

Neutrophils are autonomous cells, freely living within humans (and other mammals), which are responsible for combating infection by microbes. They are also responsible for causing damage to the host in inflammatory disease. Understanding how these cells interpret the environment and decide on an appropriate course of action is therefore vital for understanding both physiological and pathological inflammation. This report provides an overview of the intracellular signalling events within neutrophils which regulate their activity, including oxidase activation and ""priming.""

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Author:   M.B. Hallett (University of Wales College of Medicine, Cardiff) ,  D. Lloyds (University of Cardiff)
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
ISBN:  

9783540631262


ISBN 10:   3540631267
Pages:   180
Publication Date:   01 September 1997
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Physiology and pathology of neutrophils; membrane receptors on neutrophils; Ca2+ homeostasis in neutrophils; the cystolic Ca2+ signal in neutrophils; serine phosphorylation in neutrophils; tyrosine phosphorylation in neutrophils; other molecular signals in neutrophils; neutrophil cytoskeleton; integrated view of neutrophil oxidase activation and priming .

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