Overview

Written by 38 specialists and enriched with illustrations and 1900 references, this study highlights research on lanthanides and their interrelations with biosystems. It emphasizes the impact of these metals in biochemical, biological, and medical research, including the use of lanthanide ions in magnetic resonance imaging (MRI).

Full Product Details

Author:   Helmut Sigel (University of Basel, Switzerland University of Basel, Switzerland) ,  Helmut Sigel (University of Basel, Switzerland)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:  
Dimensions:   Width: 21.00cm , Height: 24.20cm , Length: 28.00cm
Weight:   1.496kg
ISBN:  

9780824742454

ISBN 10:   0824742451
Pages:   860
Publication Date:   27 March 2003
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Distribution of the Lanthanides in the Earth's Crust; Mobilization of Lanthanides through the Terrestrial Biosphere; Complexes of Lanthanide Ions with Amino Acids, Phosphates, and Other Ligands of Biological Interest in Solution; Biologically Relevant Structural Coordination Chemistry of Simple Lanthanide Ion Complexes; Lanthanide Ions as Probes in Studies for Metal Ion-Dependent Enzymes; Lanthanide Chelates as Fluorescence Labels for Diagnostics and Biotechnology; Responsive Luminescent Lanthanide Complexes; Lanthanide Ions as Probes of Electron Transfer in Proteins; Lanthanide Ions as Luminescent Probes of Proteins and Nucleic Acids; Lanthanide-Promoted Peptide Bond Hydrolysis; Lanthanide-Catalyzed Hydrolysis of Phosphate Esters and Nucleic Acids; Sequence-Selective Scission of DNA and RNA by Lanthanides and Their Complexes; Lanthanide Ions as Probes for Metal Ions in the Structure and Catalytic Mechanism of Ribozymes; Lanthanides as Shift and Relaxation Agents in Elucidating the Structure of Proteins and Nucleic Acids; Lanthanide Ions as Magnetic Resonance Imaging Agents. Nuclear and Electronic Relaxation Properties. Applications; Interactions of Lanthanides and Their Complexes with Proteins. Conclusions Regarding Magnetic Resonance Imaging.

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Helmut Sigel, University of Basel, Switzerland.

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