The Kinetochore:: From Molecular Discoveries to Cancer Therapy
Author:   Peter De Wulf ,  William Earnshaw
Publisher:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2009
ISBN:  

9781441923981


Pages:   516
Publication Date:   24 December 2010
Format:   Paperback
Availability:   Out of stock   Availability explained
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The Kinetochore:: From Molecular Discoveries to Cancer Therapy


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Overview

Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.

Full Product Details

Author:   Peter De Wulf ,  William Earnshaw
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2009
Dimensions:   Width: 15.50cm , Height: 3.80cm , Length: 23.50cm
Weight:   0.807kg
ISBN:  

9781441923981


ISBN 10:   1441923985
Pages:   516
Publication Date:   24 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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