Overview

The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

Full Product Details

Author:   Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 15.20cm , Height: 1.80cm , Length: 22.90cm
Weight:   0.650kg
ISBN:  

9780123821713

ISBN 10:   0123821711
Pages:   296
Publication Date:   06 September 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9780124078673
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Introduction Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis The role of CETP in HDL metabolism The physiological role of CETP in HDL molecule metabolism HDL and reverse cholesterol transport: Physiological modulation Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL Apoliopoprotein A-I mutations The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease Sterol efflux by ABCA1 and ABCG1 Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases Pre¿1-HDL: Conversion to and from spherical ¿-migrating HDL in human plasma Determination of circulating native and denaturated HDL concentrations and its clinical implications  

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Author Information

Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.

Tab Content 6

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