Overview

The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

Full Product Details

Author:   Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan) ,  Tsugikazu Komoda (Visiting Professor, Toho University School of Medicine, Japan)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   2nd edition
Dimensions:   Width: 15.20cm , Height: 2.30cm , Length: 22.90cm
Weight:   0.660kg
ISBN:  

9780124078673

ISBN 10:   0124078672
Pages:   354
Publication Date:   06 November 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9780128125137
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis 2. The role of CETP in HDL metabolism 3. The physiological role of CETP in HDL molecule metabolism 4. HDL and reverse cholesterol transport: Physiological modulation 5. Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress 6. Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL 7. Apoliopoprotein A-I mutations 8. The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling 9. HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease 10. Sterol efflux by ABCA1 and ABCG1 11. Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases 12. Pre?1-HDL: Conversion to and from spherical ?-migrating HDL in human plasma 13. Determination of circulating native and denaturated HDL concentrations and its clinical implications

Reviews

Editor Komoda's research handbook for physicians and medical scientists addresses in detail the biochemistry and pathophysiology of high-density lipoprotein (HDL) cholesterol. The history of HDL research is summarized in the introduction, including its labeling as good cholesterol and recent questions problematizing that label. --ProtoView.com, January 2014 This is one of the best available sources for a concise yet detailed review of the enormous data on HDL mechanics, genetics, and clinical implications...a very effective and focused presentation for a complex topic...This is an outstanding work. The book is unique in that it not only updates leaders in the field on new advances in HDL research, but it also can jump start beginners in the field. Rating: 4 Stars--Doody.com, February 28, 2014

This is one of the best available sources for a concise yet detailed review of the enormous data on HDL mechanics, genetics, and clinical implications.a very effective and focused presentation for a complex topic.This is an outstanding work. The book is unique in that it not only updates leaders in the field on new advances in HDL research, but it also can jump start beginners in the field. Rating: 4 Stars--Doody.com, February 28, 2014

Author Information

Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.

Tab Content 6

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