Overview

Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.

Full Product Details

Author:   Isabel Varela-Nieto ,  Julie Ann Chowen
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Edition:   2005 ed.
Dimensions:   Width: 17.80cm , Height: 2.20cm , Length: 25.40cm
Weight:   0.817kg
ISBN:  

9781461498117

ISBN 10:   1461498112
Pages:   421
Publication Date:   02 December 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Basic Physiology of the Growth Hormone/Insulin-Like Growth Factor Axis.- Experimental Models for Understanding the Role of Insulin-like Growth Factor-I and Its Receptor During Development.- Insulin-like Growth Factor Binding Proteins in Development.- Growth Hormone, Insulin-like Growth Factors and the Female Reproductive System.- Skeletal Muscle.- Cardiovascular and Respiratory Systems.- Hematopoiesis.- Brain Development.- Regulation of Vertebrate Sensory Organ Development: A Scenario for Growth Hormone and Insulin-Like Growth Factors Action.- Role of Insulin-Like Growth Factors in Neuronal Plasticity and Neuroprotection.- Aging and Life Span.- Interactions of Insulin-Like Growth Factor-I and Estrogen in the Brain.- Cancer.- Genetic Basis of Proportional Short Stature.- Future Perspectives.

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