Overview

Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms. Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Full Product Details

Author:   Douglas T. Carrell ,  Douglas T. Carrell
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2007 ed.
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.678kg
ISBN:  

9781588298638

ISBN 10:   1588298639
Pages:   337
Publication Date:   28 November 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Methods and Tools for the Study.- The Genetics of Male Infertility in the Era of Genomics.- The Use of cDNA Libraries to Demonstrate a Linkage Between Transcription and Translation in Male Germ Cells.- Considerations When Using Array Technologies for Male Factor Assessment.- Microarray Analysis of a Large Number of Single-Nucleotide Polymorphisms in Individual Human Spermatozoa.- Physiological and Proteomic Approaches to Understanding Human Sperm Function.- Genetics of Idiopathic Male Infertility.- Meiosis and Errors of Meiosis.- The Immunocytogenetics of Human Male Meiosis.- The Clinical Relevance of Sperm Aneuploidy.- DNA Repair Genes and Genomic Instability in Severe Male Factor Infertility.- The Y Chromosome, Development Spermatogenesis, and Sperm Maturation.- Germ Cell-Specific Genes and Posttranscriptional Regulation in the Testis.- The Genetics of Cryptorchidism.- The Chromatoid Body and microRNA Pathways in Male Germ Cells.- Sperm Maturation in the Epididymis.- Clinical Applications of the Study of the Genetics of Male Infertility.- The Structure of the Y Chromosome and Its Role in Male Infertility.- Y Chromosome Microdeletions and Haplotypes.- The Genetics of Male Infertility.- The Future of the Diagnosis of Male (In) Fertility.- Polymorphisms and Male Infertility.- The Genetics of Abnormal Protamine Expression.- Chromatin Damage and Male Infertility.- Clinical Evaluation of the Genetics of Male Infertility.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions