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Full Product Details

Author:   Lakshmi A. Devi
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2005 ed.
Dimensions:   Width: 17.80cm , Height: 3.20cm , Length: 25.40cm
Weight:   1.005kg
ISBN:  

9781588293657

ISBN 10:   1588293653
Pages:   412
Publication Date:   01 May 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

GPCRs: Structure and Function.- Structure—Function Relationships in G Protein-Coupled Receptors.- Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors.- GPCR Folding and Maturation.- Regulated Membrane Trafficking and Proteolysis of GPCRs.- GPCR Activity and Its Regulators.- Heterotrimeric G Proteins and Their Effector Pathways.- RGS Proteins.- G Protein-Coupled Receptor Kinases.- Regulators of GPCR Activity.- GPCR Interacting Proteins.- GPCR Dimerization/Oligomerization.- Biophysical and Biochemical Methods to Study GPCR Oligomerization.- Oligomerization Domains of G Protein-Coupled Receptors.- Functional Complementation and the Analysis of GPCR Dimerization.- The Role of Oligomerization in G Protein-Coupled Receptor Maturation.- Receptor Oligomerization and Trafficking.- Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization.- Recent Developments in Drug Discovery.- Role of Heteromeric GPCR Interactions in Pain/Analgesia.- Conformational Plasticity of GPCR Binding Sites.- De-Orphanizing GPCRs and Drug Development.

Reviews

.,. provides an excellent resource to introduce the reader to many of the diverse areas and questions that drive research in the GCPR field. -TRENDS in Endocrinology and Metablosim

...provides an excellent resource to introduce the reader to many of the diverse areas and questions that drive research in the GCPR field. -TRENDS in Endocrinology and Metablosim

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