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OverviewThrough the use of dramatic narratives, The Drama of DNA brings to life the complexities raised by the application of genomic technologies to health care and diagnosis. This creative, pedagogical approach shines a unique light on the ethical, psychosocial, and policy challenges that emerge as comprehensive sequencing of the human genome transitions from research to clinical medicine. Narrative genomics aims to enhance understanding of how we evaluate, process, and share genomic information, and to cultivate a deeper appreciation for difficult decisions encountered by health care professionals, bioethicists, families, and society as this technology reaches the bedside. This innovative book includes both original genomic plays and theatrical excerpts that illuminate the implications of genomic information and emerging technologies for physicians, scientists, counselors, patients, blood relatives, and society. In addition to the plays, the authors provide an analytical foundation to frame the many challenges that often arise. Full Product DetailsAuthor: Karen H. Rothenberg (Senior Advisor on Genomics and Society, Senior Advisor on Genomics and Society, National Human Genome Research Institute, Bethesda, Maryland, USA) , Lynn Wein Bush (Faculty of Pediatric Clinical Genetics, Faculty of Pediatric Clinical Genetics, Columbia University Medical Center, New York, USA)Publisher: Oxford University Press Inc Imprint: Oxford University Press Inc Dimensions: Width: 23.10cm , Height: 2.00cm , Length: 15.50cm Weight: 0.318kg ISBN: 9780199309351ISBN 10: 0199309353 Pages: 240 Publication Date: 15 May 2014 Audience: Professional and scholarly , College/higher education , Professional & Vocational , Undergraduate Format: Paperback Publisher's Status: Active Availability: To order ![]() Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of Contents"Contents Foreword Eric D. Green, MD, PhD Preface Karen H. Rothenberg & Lynn W. Bush Chapter 1 SETTING THE GENOMIC STAGE: Why Genomics, Why Narratives, Why Now? Exploring Ethical, Psychosocial & Policy Challenges of Next-Gen Sequencing Part I Narrative Genomics: Exploring Process in Context Chapter 2 ANTICIPATING THE FUTURE: Genomic Protocols & Ethics Consultations Scene I The IRB Meeting Scene II The Genomic Advisory Committee Additional Questions Chapter 3 INFORMING THE FUTURE: The Process of Consent & Disclosure of Genomic Information Scene I The Informed Consent Process Scene II The Return of Genomic Findings Additional Questions Chapter 4 REFRAMING AN ""OPEN FUTURE"": The Shifting Landscape From NBS to NBSeq Scene I The Paradoxes of NBSeq Scene II The Practical Concerns in ""Pandora's Box"" Additional Questions Part II Integrating Narrative Genomics: A Case Study Drama Chapter 5 RECONCEPTUALIZING THE PAST, PRESENT & FUTURE: Next Gen Sequencing - ""What's Next?!"" Scene I The IRB Deliberation Scene II The Informed Consent Process Scene III The Clinical Ethics Consultation Scene IV The Return of Genomic Findings Additional Questions Part III Narrative Genomics on Stage: DNA, Society & Theatre Chapter 6 DRAMATIZING THE PAST, PRESENT & FUTURE: Theatrical Narratives from Genetics to Genomics Section I The Theatrical Double Helix & ""Chromozones"" Section II Mapping & Manipulating Fate Section III A Genomic Crystal Ball in the Post-Mapping Decade Additional Questions References Bibliography Online Links to Original Genomic Plays Chapter 2 ""Imagining a Genomic Crystal Ball"" Chapter 3 ""It's Not That Simple!"" and ""It's So Complicated!!"" (sequel) Chapter 4 ""The Paradoxes in Pandora's Box"" and ""Paradoxes Within Pandora's Box"" (fuller version) Chapter 5 ""What's Next?!"""ReviewsAuthor InformationLynn Wein Bush, PhD, MS, MA is on the faculty of Pediatric Clinical Genetics at Columbia University Medical Center, a faculty associate at their Center for Bioethics, and serves as an ethicist on pediatric and genomic advisory committees for numerous academic medical centers and professional organizations. Dr. Bush has an interdisciplinary graduate background in clinical and developmental psychology, bioethics, genomics, public health, and neuroscience that informs her research, writing, and teaching on the ethical, psychological, and policy challenges of genomic medicine and clinical research with children, and prenatal-newborn screening and sequencing. Karen H. Rothenberg, JD, MPA serves as Senior Advisor on Genomics and Society to the Director, National Human Genome Research Institute and Visiting Scholar, Department of Bioethics, Clinical Center, National Institutes of Health. She is the Marjorie Cook Professor of Law, Founding Director, Law & Health Care Program and former Dean, University of Maryland Francis King Carey School of Law and Visiting Professor, Johns Hopkins Berman Institute of Bioethics. Professor Rothenberg has served as Chair of the Maryland Stem Cell Research Commission, President of the American Society of Law, Medicine and Ethics, and has been on many NIH expert committees, including the NIH Recombinant DNA Advisory Committee. Tab Content 6Author Website:Countries AvailableAll regions |