Overview

A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Full Product Details

Author:   Pedro Cortes
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1st ed. Softcover of orig. ed. 2006
Dimensions:   Width: 17.80cm , Height: 3.00cm , Length: 25.40cm
Weight:   1.097kg
ISBN:  

9781617376788

ISBN 10:   1617376787
Pages:   564
Publication Date:   09 November 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Basic Pathophysiology and Biochemistry of Diabetic Nephropathy.- Angiotensin II and Its Receptors in the Pathogenesis of Diabetic Nephropathy.- Altered Renal Microvascular Function in Early Diabetes.- Proteinuria and Interstitial Fibrogenesis in Diabetic Nephropathy.- Podocytes and Diabetic Nephropathy.- Altered Glucose Transport and Its Metabolic Effects in Glomerular Cells.- mRNA Translation in Diabetic Nephropathy.- The Hexosamine Biosynthesis Pathway.- Glycation.- Oxidative and Glycooxidative Stress in Diabetic Nephropathy.- Connective Tissue Growth Factor in the Pathogenesis of Diabetic Nephropathy.- Vascular Endothelial Growth Factor as a Determinant of Diabetic Nephropathy.- Transforming Growth Factor-? Signal Transduction in the Pathogenesis of Diabetic Nephropathy.- Hepatocyte Growth Factor.- Proteomics in the Investigation of Diabetic Nephropathy.- Gene Expression Profiling in the Investigation of Diabetic Nephropathy.- PPAR-? Ligands and Diabetic Nephropathy.- ?-Endosulfine in Diabetic Nephropathy.- The Prospect of a Novel Therapeutic, Bone Morphogenetic Protein-7, in Diabetic Nephropathy.- Clinical Aspects of Diabetic Nephropathy.- Genetic Determinants of Diabetic Nephropathy in Type 2 Diabetes.- Major Risks Indicators for Diabetic Kidney Disease.- The Structure of Human Diabetic Nephropathy.- Diabetic Kidney Disease in Transitional and Disadvantaged Populations.- Screening and Treatment of Early Diabetic Renal Disease in Type 1 and Type 2 Diabetes.- Treatment in Advanced Renal Disease in Type 1 and Type 2 Diabetes.- Diabetic Renal and Related Heart Disease.- Management of Diabetic End-Stage Renal Disease With Dialysis.- Diabetic Retinopathy and Nephropathy.- Hypertension and Cardiovascular Disease.- Endothelial Dysfunction.- Anemia and DiabeticNephropathy.

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