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OverviewA comprehensive review of recent scientific evidence examining the contributions of animal experimentation to human healthcare. The book also explores toxicity prediction, animal use during life and health sciences education, impacts on student attitudes toward animals, and the extent to which animals suffer in laboratories. Full Product DetailsAuthor: Andrew KnightPublisher: Palgrave Macmillan Imprint: Palgrave Macmillan Dimensions: Width: 14.00cm , Height: 1.40cm , Length: 21.60cm Weight: 0.349kg ISBN: 9781137289681ISBN 10: 1137289686 Pages: 254 Publication Date: 27 May 2011 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsList of Tables List of Figures List of Abbreviations Acknowledgements Series Preface Introduction PART I ANIMAL COSTS Global Laboratory Animal Use Types of Laboratory Animal Use mpacts on Laboratory Animals PART II HUMAN BENEFITS Human Clinical Utility of Animal Models Human Toxicological Utility of Animal Models Factors Limiting the Human Utility of Animal Models PART III ALTERNATIVE STRATEGIS Non-Animal Research and Testing Methodologies Reduction and Refinement of Laboratory Animal Use PART IV EDUCATIONAL ANIMAL USE AND STUDENT IMPACTS Educational Animal Use Effects of Harmful Animal Use on Students PART V CONCLUSIONS AND POLICY RECOMMENDATIONS The Costs and Benefits of Animal Experimentation 13 Regulatory Developments and Policy Recommendations Contents Glossary References IndexReviews'This is an important addition to the animal protection literature. This well referenced and documented text includes a significant amount of data in theform of easily readable tables and figures. The arguments are well made and informative. The conclusions are no surprise but go beyond telling us what is wrong but points to directions that can be followed. This is an appropriate text and reference for those on all sides of the issue.' - Alan M Goldberg Ph.D. Professor of Toxicology Chairman of the Board, Center for Alternatives to Animal Testing Bloomberg School of Public Health, Johns Hopkins University USA 'Andrew Knight has done an excellent job in pulling together a large number of publications relating to animal use both for clinical research and education. The book is well written, well organized, well referenced and very readable. It presents a reasonably balanced view and makes strong arguments, based on a sound evidence base, for discontinuing animal experiments in both clinical research and education. For me the education section was a little too biased towards veterinary education but this is a minor criticism. An excellent introduction to the topic.' - Professor David Dewhurst BSc PhD, Professor of e-learning and Jeanne MarchigProfessorial Fellow of Replacement Alternatives in Higher Education, University of Edinburgh, UK '[Knight] draws on more than a decade of research and over 500 scientific publications to rigorously test common assumptions about animal experimentation. He offers revealing insights into the true contributions of such research to human healthcare, as well as the nature, severity and prevalence of the impacts experienced by laboratory animals. He comprehensively reviews animal use within life and health sciences education, as well as alternative research and educational strategies. This has allowed him to provide, in polished style, one of the most definitive answers yet published to a question with implications for animal ethics, biomedical research, and society at large, namely, Is animal experimentation ethically justifiable? His highly readable book is destined to remain an essential text for all who are interested in the ethical issues raised by animal experimentation, including scientists, philosophers, policy-makers, students, and educators.' - Marc Bekoff, Psychology Today, 2012 'Animal experimentation is invariably given a utilitarian justification: the overall good outweighs the overall evil. Knight's work is the definitive reply to such reasoning. He clearly demonstrates that rigorous examination and analysis of the data simply do not support such traditional, untested assumptions. Deftly written, the book is highly recommended to scientists, philosophers, veterinarians, students, and indeed any layperson with concerns regarding the morality of experimenting on nonhuman animals.' - Professor Mark H. Bernstein, Purdue University College of Liberal Arts, USA 'A timely and valuable contribution to the debate surrounding the use of animals in research. What makes this book stand apart from other similar works is its focus on evidence-based science. This book makes this important information easily accessible to both regulators and researchers. The wide range of topics covered in the book will also provide animal ethics committees with valuable new insights into cost-benefit assessments. This book should be required reading for undergraduate students intending to use animals as part of their course work. It should also serve as required reading for members of animal ethics committees whose remit is to review animal research proposals.' - Andre Menache, Veterinary Practice, 2011 'Knight presents a wealth of data on the issue of costs and benefits associated with animal experiments and the book goes beyond its title: it also imparts some information on alternatives... The format is excellent for a reader that may not wish to peruse the book from cover to cover as it is very well structured with chapters, each containing introductions, descriptive/informative sub-headings and useful summaries, making navigation through the book very easy. Some information is repeated, which means that chapters can be read stand-alone... The book is a good starting point for a critical reader looking for an introduction to the subject area.' - Susanne Prankel, Animals, 2012 'Using a wealth of scientific information, Dr. Knights' book provides a critical and thorough examination of the topic of animal experimentation. The book is excellently organized and easy to follow. I highly recommend this book to anyone interested in medical research and human health.' - Aysha Akhtar, Food and Drug Administration, USA 'An excellent critical review that boosts further discussions on the cost and benefits of animal experimentation. A 'must' for members of animal ethics committees.' - Jan van der Valk, Utrecht University, The Netherlands 'Provides excellent background reading on the subject.' - Pete Wedderburn, The Telegraph, 2011 '...well worth reading...' - Anthrozoos '[Knight] draws on more than a decade of research and over 500 scientific publications to rigorously test common assumptions about animal experimentation. He offers revealing insights into the true contributions of such research to human healthcare, as well as the nature, severity and prevalence of the impacts experienced by laboratory animals. He comprehensively reviews animal use within life and health sciences education, as well as alternative research and educational strategies. This has allowed him to provide, in polished style, one of the most definitive answers yet published to a question with implications for animal ethics, biomedical research, and society at large, namely, Is animal experimentation ethically justifiable? His highly readable book is destined to remain an essential text for all who are interested in the ethical issues raised by animal experimentation, including scientists, philosophers, policy-makers, students, and educators.' - Marc Bekoff, Psychology Today, 2012 'Animal experimentation is invariably given a utilitarian justification: the overall good outweighs the overall evil. Knight's work is the definitive reply to such reasoning. He clearly demonstrates that rigorous examination and analysis of the data simply do not support such traditional, untested assumptions. Deftly written, the book is highly recommended to scientists, philosophers, veterinarians, students, and indeed any layperson with concerns regarding the morality of experimenting on nonhuman animals.' - Professor Mark H. Bernstein, Purdue University College of Liberal Arts, USA 'A timely and valuable contribution to the debate surrounding the use of animals in research. What makes this book stand apart from other similar works is its focus on evidence-based science. This book makes this important information easily accessible to both regulators and researchers. The wide range of topics covered in the book will also provide animal ethics committees with valuable new insights into cost-benefit assessments. This book should be required reading for undergraduate students intending to use animals as part of their course work. It should also serve as required reading for members of animal ethics committees whose remit is to review animal research proposals.' - Andre Menache, Veterinary Practice, 2011 'Knight presents a wealth of data on the issue of costs and benefits associated with animal experiments and the book goes beyond its title: it also imparts some information on alternatives... The format is excellent for a reader that may not wish to peruse the book from cover to cover as it is very well structured with chapters, each containing introductions, descriptive/informative sub-headings and useful summaries, making navigation through the book very easy. Some information is repeated, which means that chapters can be read stand-alone... The book is a good starting point for a critical reader looking for an introduction to the subject area.' - Susanne Prankel, Animals, 2012 'Using a wealth of scientific information, Dr. Knights' book provides a critical and thorough examination of the topic of animal experimentation. The book is excellently organized and easy to follow. I highly recommend this book to anyone interested in medical research and human health.' - Aysha Akhtar, Food and Drug Administration, USA 'An excellent critical review that boosts further discussions on the cost and benefits of animal experimentation. A 'must' for members of animal ethics committees.' - Jan van der Valk, Utrecht University, The Netherlands 'Provides excellent background reading on the subject.' - Pete Wedderburn, The Telegraph, 2011 '...well worth reading...' - Anthrozoos Author InformationAndrew Knight is a European Veterinary Specialist in Welfare Science, Ethics and Law, and a Fellow of the Oxford Centre for Animal Ethics, UK, and an Associate Professor of Welfare and Ethics at Ross University School of Medicine in the Caribbean. Tab Content 6Author Website:Countries AvailableAll regions |