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OverviewFirst published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes. These compounds occur in smoke and mineral oils and a few have been shown to be potent carcinogens. This volume was the first to review, systematically and in depth, the organic synthesis of these compounds as well as their metablolism, interactions with nucleic acids and protein, mutagenicity and carcinogenicity. Such studies have important implications in determining mechanism and specificity of chemically induced carcinogenesis. Full Product DetailsAuthor: M. S. Newman , B. Tierney , S. VeeraraghavanPublisher: Cambridge University Press Imprint: Cambridge University Press (Virtual Publishing) ISBN: 9780511753183ISBN 10: 0511753187 Publication Date: 07 September 2010 Audience: Professional and scholarly , Professional & Vocational Format: Undefined Publisher's Status: Active Availability: Available To Order ![]() We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsPart I. Chemistry: 1. Synthetic routes from benzenes and naphthalenes; 2. Synthetic routes from anthracenes (A-ring formation); 3. Synthetic routes from anthracenes (D-ring formation); Part II. Biology: 8. Metabolism; 9. DNA, RNA and protein interactions; 10. Mutagenicity; 11. Carciogenicity; References; Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |