Overview
Section 1: The Degradome and its analysis Chapter 1: Protease Genomics and the Cancer Degradome Xose S. Puente, Gonzalo R Ordonez & Carlos López-Otín Chapter 2: The CLIP-CHIP: A focused oligonucleotide microarray platform for transcriptone analysis for the complete human and murine cancer degradomes. Rheinhild Kappelhoff, Claire H.Wilson, & Christopher M. Overall Chapter 3: The Hu/Mu ProtIn chip: A custom dual-species Oligonucleotide Microarray for profiling degradome gene expression in tumours and their microenvironment Donald R.Scwartz, Kamiar Moin, Ekkehard Weber & Bonnie F Sloane Chapter 4: Quantitative Real-Time PCR analysis of degradome gene expression Caroline J Pennington, Robert K. Nuttall, Clara Sampieri -Ramirez, Matthew Wallard, Simon Pilgrim & Dylan R. Edwards Chapter 5: Identification of protease substrates by mass spectrometry approaches. Mari Enoksson, Wenhong Zhu & Guy Salvesen Chapter 6: Identification of protease substrates by mass spectrometry approaches - 2. Anna Prudova, Ulrich auf dem Keller & Christopher M. Overall Chapter 7: Activity based imaging and biochemical profiling tools for analysis of the cancer degradome. Vincent Dive, Margot Paulick, J.Oliver McIntyre, Lynn M. Matrisan & Matthew Bogyo. Chapter 8: Images of cleavage Kamiar Moin, Mansoureh Sameni, Christopher Jedeszko, Quanwen Li, Mary B. Olive, Raymond R. Mattingly & Bonnie F. Sloane Section 2: Insights into Protease function Chapter 9: Proteolytic pathways: Intersecting cascades in cancer development Nesrine I. Affara & Lisa M, Coussens Chapter 10: Physiological functions of plasminogen activation: Effects of gene deficiences in humans andmice Thomas H. Bugge Chapter 11: The plasminogen activation system in tissue remodelling and cancer invasion Kasper Almholt, Anna Juncker-Jensen, Kirsty Anne Green, Helene Solberg, Leif Roge Lund & John Rømer Chapter 12: The urokinase plasminogen activator receptor as a target for cancer therapy Silvia D'Alessio & Francesco Blasi Chapter 13: The endocytic collagen receptor uPARAP/Endo 180 in cancer invasion and tissue remodelling Thore Hillig, Lars H. Engelholm & Niels Behrendt Chapter 14: Physiological and pathological functions of type II transmembrane serine proteinases: Lessons from transgenic mouse models and human disease-associated mutations. Karin List & Thomas Bugge Chapter 15: Analysis of cysteine cathepsin knockout mice in cancer models Thomas Reinheckel, Vasilena Gocheva, Christoph Peters & Johanna A. Joyce Chapter 16: In vitro and in vivo models of angiogenesis to dissect MMP functions. Sarah Berndt, Françoise Bruyère, Maud Jost & Agnès Noël Chapter 17: The surface transplantation model to study the tumour-host interface Maud Jost, Silvia Vosseler, Silvia Blacher, Norbert E. Fusenig, Margareta Mueller & Agnes Noel Chapter 18: Unravelling the roles of proteases in cell migration in vitro and in vivo Jelena Gavrilovic & Xanthe Scott Chapter 19: New insights into MMP function in adipogenesis Kumari L Andarawewal & Marie-Christine Riol Chapter 20: TIMPs: Extracellular Modifiers in Cancer Development Aditya Murty, William Cruz-Munoz & Rama Khokha Section 3: The interface between Proteolysis and Cell Signalling Chapter 21: Invadopodia: Interface for Invasion Susette C Mueller, Vira V. Artym
Full Product Details
Author: Dylan Edwards ,
Gunilla Hoyer-Hansen ,
Francesco Blasi ,
B.F. Sloane
Publisher: Springer-Verlag New York Inc.
Imprint: Springer-Verlag New York Inc.
Edition: Softcover Reprint of the Original 1st 2008 ed.
Dimensions:
Width: 15.50cm
, Height: 4.90cm
, Length: 23.50cm
Weight: 1.980kg
ISBN: 9781493938865
ISBN 10: 149393886
Pages: 926
Publication Date: 23 August 2016
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
