Awards

• Winner of Choice Outstanding Academic Title 2022

Overview

Pain is an inevitable part of existence, but severe debilitating or chronic pain is a pathological condition that diminishes the quality of life. The Brain and Pain explores the present and future of pain management, providing a comprehensive understanding based on the latest discoveries from many branches of neuroscience. Richard Ambron-the former director of a neuroscience lab that conducted leading research in this field-explains the science of how and why we feel pain. He describes how the nervous system and brain process information that leads to the experience of pain, detailing the cellular and molecular functions that are responsible for the initial perceptions of an injury. He discusses how pharmacological agents such as opiates affect the duration and intensity of pain. Ambron examines new evidence showing that discrete circuits in the brain modulate the experience of pain in response to a placebo, fear, anxiety, belief, or other circumstances, as well as how pain can be relieved by activating these circuits using mindfulness training and other nonpharmacological treatments. The book also evaluates the prospects of procedures such as deep brain stimulation and optogenetics. Current and thorough, The Brain and Pain will be invaluable for a range of people seeking to understand their options for treatment as well as students in neuroscience and medicine.

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9780231204866

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Reviews

The Brain and Pain is a comprehensive review of the fundamental principles of pain neurobiology and electrophysiology, with interesting viewpoints on pain psychology and philosophy. -- Carl Saab, Director of Pain Science, Technology And Research (STAR) Lab, Cleveland Clinic, Professor at Case Western Reserve University, adjunct Professor at Brown University.

The Brain and Pain is a comprehensive review of the fundamental principles of pain neurobiology and electrophysiology, with interesting viewpoints on pain psychology and philosophy. -- Carl Saab, Director of Pain Science, Technology And Research (STAR) Labs, Cleveland Clinic, Professor at Case Western Reserve University, adjunct Professor at Brown University This book may be of specific interest to students at any level who are interested in medicine, neuroscience, or biology but should also be accessible to anyone interested in the mechanisms of pain perception and treatment, provided they do not mind learning some biology on the way. * Choice *

Author Information

Richard Ambron is emeritus professor of pathology, anatomy, and cell biology at the Vagelos College of Physicians and Surgeons of Columbia University, where he codirected the clinical anatomy course for first-year medical and dental students. For forty years, he directed a laboratory that investigated the molecular bases of nerve regeneration and the molecular pathways responsible for pain.

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