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Author:   Jr. Ruffolo
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1987 ed.
Dimensions:   Width: 15.20cm , Height: 3.10cm , Length: 22.90cm
Weight:   0.968kg
ISBN:  

9780896031104

ISBN 10:   0896031101
Pages:   544
Publication Date:   08 January 1988
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Section 1: Historical Perspectives.- 1 alpha-1 Adrenergic Receptors: A Historical Perspective.- Section 2: Characterization of the Receptor and Its Binding Site.- 2 Biochemistry and Pharmacology of the alpha-1 Adrenergic Receptor.- 3 Localizing the alpha-1 Adrenergic Receptor in the Central Nervous System: Relating Pharmacology to Structure and Function.- Section 3: Biochemical Mechanism of Receptor Action.- 4 Ca2+ Utilization in Signal Transformation of alpha-1 Adrenergic Receptors.- 5 Phosphoinositides and alpha-1 Adrenergic Receptors.- Section 4: Correlation of Receptor Binding and Function.- 6 Structure-Activity Relationships for alpha-1 Adrenergic Receptor Agonists and Antagonists.- 7 Relationship of alpha-1 Adrenergic Receptor Occupancy to Tissue Response.- 8 Heterogeneity of alpha-1 Adrenergic Receptors.- 9 Heterogeneity of alpha-Adrenergic Responsiveness in Vascular Smooth Muscle: Role of Receptor Subtypes and Receptor Reserve.- 10 alpha-1 Adrenergic Receptors in the Central Nervous System.- Section 5: Regulation of alpha-1 Adrenergic Receptors.- 11 Regulation of alpha-1 Adrenergic Receptors.- Section 6: Agents Interacting with alpha-1 Adrenergic Receptors.- 12 Therapeutic Applications of Agents Interacting with alpha-1 Adrenergic Receptors.- Section 7: Future Vistas.- 13 alpha-1 Adrenergic Receptors: Summary and Future Vistas.

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