The Aetiology of Deep Venous Thrombosis: A Critical, Historical and Epistemological Survey

Author:   P. Colm Malone ,  Paul S. Agutter
Publisher:   Springer-Verlag New York Inc.
Edition:   2008 ed.
ISBN:  

9781402066498


Pages:   318
Publication Date:   24 January 2008
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Our Price $393.36 Quantity:  
Add to Cart

Share |

The Aetiology of Deep Venous Thrombosis: A Critical, Historical and Epistemological Survey


Add your own review!

Overview

What we now call ‘deep venous thrombosis’ (DVT) has been studied in diverse ways during the last 200–300 years. Each of these approaches contributes to a full modern understanding of aetiology. Therefore, much of this book is a historical survey of the field. However, our remit is broader than the title might suggest: the evolution of ideas about DVT is typical in many ways of medical biology as a whole. Thus, although the aetiology of DVT may seem a narrow topic for a monograph – it implicitly excludes arterial thrombosis and marginalises prophylaxis, therapy, and even such clinically significant sequelae as pulmonary embolism – we hope to engage the reader in a much more general inquiry. Our historical investigation reveals a 160-year-old schism between two contrasting philosophies of medical and biological research, a schism that is particularly – but by no means uniquely – relevant to the study of DVT. In principle, these philosophies should be complementary rather than competing. So while we wish to elucidate the aetiology of DVT per se, we are also concerned with a more abstract and wide-ranging issue: the future accommodation or rapprochement between two conceptual and methodological traditions.

Full Product Details

Author:   P. Colm Malone ,  Paul S. Agutter
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2008 ed.
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   0.682kg
ISBN:  

9781402066498


ISBN 10:   140206649
Pages:   318
Publication Date:   24 January 2008
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

to the Study of Deep Venous Thrombosis.- The Coagulation Cascade and the Consensus Model of DVT.- Hypercoagulability.- Historical Roots.- Coagulation and its Disorders: A History of Haematological Research.- Virchow and the Pathophysiological Tradition in the 19th Century.- The Pathophysiological Tradition after Virchow.- Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves.- Underperfusion of Valve Pockets and the Initiation of DVT.- The Role of Endothelial Hypoxia in DVT.- The Valve Cusp Hypoxia Hypothesis.- Molecular Changes in the Hypoxic Endothelium.- Cadaver Clots or Agonal Thrombi?.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions
Latest Reading Guide

MRG2025CC

 

Shopping Cart
Your cart is empty
Shopping cart
Mailing List