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Author:   C J Dorman (Univ Of Dublin, Ireland) ,  Gordon Dougan (Imperial College, Uk) ,  David W Holden (Imperial College, Uk) ,  H Smith (Univ Of Birmingham, Uk)
Publisher:   Imperial College Press
Imprint:   Imperial College Press
ISBN:  

9781860942723

ISBN 10:   1860942725
Pages:   408
Publication Date:   12 December 2001
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction: questions about the behaviour of bacterial pathogens in vivo, H. Smith; DNA topology and adaptation of Salmonella Typhimurium to an intracellular environment, D.G. Marshall et al. New methods for studying bacterial behaviour in vivo: the pathogenesis of Shigella Flexneri infection - lessons from in vitro and in vivo studies, D.J. Philpott et al; detection and analysis of gene expression during infection by in vivo expression technology, D.S. Merrell and A. Camilli; measurement of bacterial gene expression in vivo, I. Hautefort and J.C.D. Hinton; identification and analysis of bacterial virulence genes in vivo, K.E. Unsworth and D.W. Holden; Salmonella interactions with host cells - in vitro to in vivo, B.B. Finlay and J.H. Brumell. Impact of the new methods: in vivo gene expression and the adaptive response - from pathogenesis to vaccines and antimicrobials, D.M. Heithoff et al; challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens, R. Moxon and C. Tang; virulence gene regulation inside and outside, V.J. DiRita et al. Evidence for operation in vivo of aspects of pathogenicity revealed by recent work in vivo: potential use of new methods - quorum sensing and the population-dependent control of virulence, P. Williams et al; type III secretion - a bacterial device for close combat with cells of their eukaryotic host, G.R. Cornelis; evolution of microbial pathogens, J. Morschhauser et al; the immune responses to bacterial antigens encountered in vivo at mucosal surfaces, G. Dougan et al.

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