Overview

Telomeres in Health and Disease, volume 125

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9780123978981

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Reviews

Praise for the series: Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell. --British Medical Journal

PRAISE FOR THE SERIES Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell. --BRITISH MEDICAL JOURNAL

Author Information

Rodrigo Calado received his MD in 1997 and PhD in 2003 both from the University of São Paulo, Brazil. He was trained in hematology and did his postdoctoral fellowship at the U. S. National Institutes of Health in Bethesda, Maryland with Dr. Neal S. Young, where he also worked as a Staff Scientist between 2007 and 2011. He is currently Associate Professor of Medicine at the University of São Paulo in Ribeirão Preto, Brazil. Dr. Calado was the first to report on telomerase enzyme mutations in humans causing disease (aplastic anemia) and found that telomerase complex mutations also predisposed to leukemia and liver cirrhosis. He also demonstrated that short telomeres increase chromosome instability in humans and that sex hormones up-regulate telomerase function in hematopoietic cells.

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