Targeted Therapies: Mechanisms of Resistance

Author:   Daniel Gioeli
Publisher:   Humana Press Inc.
Edition:   2011
ISBN:  

9781607614777


Pages:   202
Publication Date:   29 June 2011
Format:   Hardback
Availability:   In Print   Availability explained
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Targeted Therapies: Mechanisms of Resistance


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Full Product Details

Author:   Daniel Gioeli
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2011
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.494kg
ISBN:  

9781607614777


ISBN 10:   1607614774
Pages:   202
Publication Date:   29 June 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Resistance to Targeted Therapies As a Result of Mutation(s) in the Target.- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies.- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry.-  Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications.-  Using Phosphoflow to Study Signaling Events of Sub Populations Resistant to Current Therapies.- Mathematical and Computational Models in Cancer.- Somatic Evolution of Acquired Drug Resistance in Cancer.- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer.- MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways.- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer.- Somatic Evolution of Acquired Drug Resistance in Cancer.- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer.- MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways.- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer.- Somatic Evolution of Acquired Drug Resistance in Cancer.- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer.- MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways.- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance.

Reviews

From the reviews: ""This is an important resource, providing a mechanistic understanding of the signaling event in cancer for developing effective targeted cancer therapies, as well as computational biology and systems theory. ! great value to oncologists and physician-scientists treating patients, and translational scientists ! . even students interested in this field will find it useful. ! an important book for understanding major mechanisms of resistance to targeted cancer therapeutic agents as well as microRNA as a potential therapy capable of targeting multiple cancer signaling pathways."" (Omer Iqbal, Doody's Review Service, September, 2011)


From the reviews: This is an important resource, providing a mechanistic understanding of the signaling event in cancer for developing effective targeted cancer therapies, as well as computational biology and systems theory. ... great value to oncologists and physician-scientists treating patients, and translational scientists ... . even students interested in this field will find it useful. ... an important book for understanding major mechanisms of resistance to targeted cancer therapeutic agents as well as microRNA as a potential therapy capable of targeting multiple cancer signaling pathways. (Omer Iqbal, Doody's Review Service, September, 2011) The book provides a well-balanced insight into the topic of drug resistance ... . the reader can find a lot of information about the progress and inspiration how to overcome the cancer resistance. The book represents a useful source of knowledge for cell and molecular biologists, geneticists, professionals in bioinformatics, researchers and physicians working in translational oncology. (J. Sedlak, Neoplasma, Issue 6, November-December, 2012)


From the reviews: This is an important resource, providing a mechanistic understanding of the signaling event in cancer for developing effective targeted cancer therapies, as well as computational biology and systems theory. ! great value to oncologists and physician-scientists treating patients, and translational scientists ! . even students interested in this field will find it useful. ! an important book for understanding major mechanisms of resistance to targeted cancer therapeutic agents as well as microRNA as a potential therapy capable of targeting multiple cancer signaling pathways. (Omer Iqbal, Doody's Review Service, September, 2011)


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