Overview

Full Product Details

Author:   Thomas F. Gajewski ,  F. Stephen Hodi
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2012
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.752kg
ISBN:  

9781617794063

ISBN 10:   1617794066
Pages:   378
Publication Date:   14 December 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

Molecular targets and subtypes in melanoma.- Melanoma genomics.- Predictive biomarkers as a guide to future therapy selection in melanoma.- KIT as a therapeutic target for melanoma.- Targeted inhibition of B-Raf.- The notch and B-catenin pathways.- STAT3 and Src signaling in melanoma.- Targeting the mTOR, PI3K and AKT pathways in melanoma.- Targeting apoptotic pathways in melanoma.- Anti-angiogenesis therapy in melanoma.- Melanoma antigens recognized by T lymphocytes.- Melanoma vaccines.- Adoptive cell therapy for the treatment of metastatic melanoma.- Anti-CTLA-4 monolonal antibodies.- Anti-PD-1 and Anti-B7-H1/PD-L1 monoclonal antibodies.- Treatment of melanoma with agonist immune co-stimulatory agents.- Novel cytokines for immunotherapy of melanoma.- Modulating the tumor microenvironment.

Reviews

From the reviews: This book is a multiauthored edition, with contributors and editors who are experts in their fields regarding new therapeutic approaches for melanoma. ... It is a highly technical volume and is directed toward true melanoma mavins, both clinical and laboratory research based, who continue to work at the translational interface. ... I recommend this to all those clinical, translational, and laboratory investigators committed to moving the field forward in the development of treatment for melanoma. (Janice P. Dutcher, Medical Oncology, Vol. 30, 2013)

From the reviews: This book is a multiauthored edition, with contributors and editors who are experts in their fields regarding new therapeutic approaches for melanoma. ... It is a highly technical volume and is directed toward true melanoma mavins, both clinical and laboratory research based, who continue to work at the translational interface. ... I recommend this to all those clinical, translational, and laboratory investigators committed to moving the field forward in the development of treatment for melanoma. (Janice P. Dutcher, Medical Oncology, Vol. 30, 2013)

From the reviews: “This book is a multiauthored edition, with contributors and editors who are experts in their fields regarding new therapeutic approaches for melanoma. … It is a highly technical volume and is directed toward true melanoma mavins, both clinical and laboratory research based, who continue to work at the translational interface. … I recommend this to all those clinical, translational, and laboratory investigators committed to moving the field forward in the development of treatment for melanoma.” (Janice P. Dutcher, Medical Oncology, Vol. 30, 2013)

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