Overview
This book addresses one of the major challenges of immunology today that is being directed to the translation of the rapidly emerging volume of basic science contributions of immunology to clinical medicine. In so doing, the book systemically introduces and discusses concepts, classifications, phenotypic and functional descriptions of regulatory T (Treg) cells in health and disease. The authors of the 15 chapters were selected from among the most qualified experts in the field of Treg cell research who provide a comprehensive overview of Treg cells and their biology in the ensuing chapters. The beginning chapters provide a useful contemporary classification of Treg cell populations and then progress to chapters that explore basic mechanisms of Treg cell function and epigenetic control. In addition to descriptions of typical CD4+ Foxp3+ cells, other chapters provide detailed presentations of Treg subsets such as CD8+ Tregs and IL-10-producing Tr1 cells. The differences of various Treg subsets, as well as circulating and resident Treg cell populations, are next compared. Importantly, the next chapters provide the clinical correlation of Treg cells with autoimmune diseases, inflammatory diseases, metabolic diseases, cancer and organ transplantation and progress to chapters that highlight emerging innovative technology including nanoparticle-Treg cells and their translational values. In summary, the book will provide a valuable resource not only for graduate students and researchers in the fields of immunology, cell biology and translational medicine but also for all others interested in learning more about Treg cells and their application in human health and disease.
Full Product Details
Author: Song-Guo Zheng
Publisher: Springer Verlag, Singapore
Imprint: Springer Verlag, Singapore
Edition: 1st ed. 2021
Volume: 1278
Weight: 0.702kg
ISBN: 9789811564093
ISBN 10: 9811564094
Pages: 302
Publication Date: 03 February 2022
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Author Information
Dr. Song-Guo Zheng is Ronald L. Whisler Chair in Immunology and Rheumatology, Professor of Internal Medicine of Ohio State University College of Medicine, USA. He is also the director of the Department of Clinical Immunology, Third Hospital affiliated to Sun Yat-sen University, China. He serves as the EiC of American Journal of Clinical and Experimental Immunology, Associate Editor of Frontiers in Immunology, and the editorial board member of several international peer-reviewed journals, such as Cytokine & Growth Factor Reviews and Cellular and Molecular Immunology. Dr. Zheng’s research group is investigating the properties of regulatory T cells (Tregs), and their role in the maintenance of immune tolerance and prevention of autoimmune diseases. He has published over 100 articles on international journals in this field.
