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Author:   Stefan F. Martin
Publisher:   Springer Basel
Imprint:   Springer Basel
Edition:   2014 ed.
Volume:   104
Dimensions:   Width: 15.50cm , Height: 1.60cm , Length: 23.50cm
Weight:   4.144kg
ISBN:  

9783034807258

ISBN 10:   3034807252
Pages:   184
Publication Date:   21 November 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

The use of T cells in Hazard Characterization of Chemical and Drug Allergens and integration in testing strategies.- Activation of the TCR complex by peptide-MHC and superantigens.- Activation of the TCR complex by small chemical compounds.- T Cell Responses to Contact Allergens.- Contact hypersensitivity: Quantitative aspects, susceptibility and risk factors.- Tools and methods for identification and analysis of rare antigen-specific T lymphocytes.- Human T cell priming assay. Depletion of peripheral blood lymphocytes in CD25+ cells improves the in vitro detection of weak allergen-specific T cells.- Correlation of contact sensitizer potency with T cell frequency and TCR repertoire diversity.- On the role of co-inhibitory molecules in dendritic cell - T helper cell co-culture assays aimed to detect chemical induced contact allergy.- T cell responses to drugs and drug metabolites.- Hypersensitivity reactions to betalactams.

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