Overview

Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon.

Full Product Details

Author:   Edison T. Liu (Genome Institute of Singapore, <i>Singapore</i>) ,  Douglas A. Lauffenburger (Massachusetts Institute of Technology, <i>Cambridge, MA, USA</i>)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 15.20cm , Height: 3.30cm , Length: 22.90cm
Weight:   0.980kg
ISBN:  

9780123725509

ISBN 10:   012372550
Pages:   448
Publication Date:   30 October 2009
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

I. Foundations of Systems Biology Genomic Technologies for Systems Biology Proteomic Technologies II. Computational Modeling of Biological Systems Dynamic Systems Analysis Spatio-temoral Modeling of Cellular Systems High-level modeling of biological networks High-Performance Computing Modeling Software III. Network Biology Protein Interaction Networks Signaling Networks with Modeling Strategies Protein networks in integrin-mediated adhesions Network Imaging RNAi networks IV. Integrative Biology of Higher Biosystems Signal Processing and Integration During Development Systems Biology and Stem Cell Biology Application of immunologic modeling in drug discovery and development V. Systems Medicine Applications Systems Pharmacology

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