Systems Biology of Apoptosis
Author:   Inna N. Lavrik
Publisher:   Springer-Verlag New York Inc.
Edition:   2013 ed.
ISBN:  

9781461440086


Pages:   204
Publication Date:   10 September 2012
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Systems Biology of Apoptosis


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Overview

Systems Biology of Apoptosis summarizes all current achievements in this emerging field. Apoptosis is a process common to all multicellular organisms. Apoptosis leads to the elimination of cells via a complex but highly defined cellular programme. Defects in the regulation of apoptosis result in serious diseases such as cancer, autoimmunity, AIDS and neurodegeneration. Recently, a substantial step forward in understanding the complex apoptotic pathways has been made by utilising systems biology approaches. Systems biology combines rigorous mathematical modelling with experimental approaches in a closed loop cycle for advancing our knowledge about complex biological processes. In this book, the editor describes the contemporary systems biology studies devoted to apoptotic signaling and focuses on the question how systems biology helps to understand life/death decisions made in the cell and to develop new approaches to rational treatment strategies.

Full Product Details

Author:   Inna N. Lavrik
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2013 ed.
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.494kg
ISBN:  

9781461440086


ISBN 10:   1461440084
Pages:   204
Publication Date:   10 September 2012
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- Modeling formalisms in systems biology of apoptosis.- Systems biology of death receptor-induced apoptosis.- Systematic complexity reduction of signaling models and application to a CD95 signaling model for apoptosis.- Systems Biology of the Mitochondrial Apoptosis Pathway.- Systems biology of cell death in hepatocytes.- Understanding different types of cell death using Systems Biology.- Modeling Single Cells in Systems Biology.- Cytokine-cytokine crosstalk and cell-death decisions.- Genetic and genomic dissection of apoptosis signaling.- Index.

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