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Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease

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Author:   Babak Sokouti (Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Iran)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.980kg
ISBN:  

9780443223266

ISBN 10:   0443223262
Pages:   354
Publication Date:   08 November 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Part 1. Introduction 1.1 Systems biology at a glance 1.2. A history on systems biology evolution 1.3. Brief information on cellular biology and signaling pathways 1.4. Systems biology: where are we? 1.5. Filling the gaps between systems biology and cell biology 1.6 Concluding remarks 1.7 Mathematical concepts 1.5. Kinetic and dynamics of biological systems Part 2. Tools and Resources 2.1. Biological data sources 2.1.1. Microarray 2.1.2. Next generation sequencing (NGS) 2.1.3. Comparative genomic hybridization (CGH) 2.1.4. Single nucleotide polymorphisms (SNP) 2.2. High throughput data 2.1.2. Databases 2.3. Programming, tools and software Part 3. Systems biology in action – to understand diseases 3.1 Big data analysis techniques 3.2 Reconstruction of genome and proteomic scale network structures and functions 3.3 Validation strategies 3.3.1 Mathematical model development 3.3.2 Biological gene expression models 3.3.3 Experimental techniques 3.4 Applications of systems biology extensions in diseases 3.4.1 Systems immunology 3.4.2 Systems pharmacology 3.4.3 Systems virology 3.4.4 Systems vaccinology 3.4.5 Systems neuroscience 3.4.6 Systems medicine 3.4.7 Future directions on systems biology

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Author Information

Dr. Sokouti is an Assistant Professor and Head of Systems Medicine, Bioinformatics, and Molecular Modeling Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences. This is his third edited book, and he has authored multiple book chapters and journal articles.

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