Awards

• Commended for BMA Medical Book Competition: Oncology 2011.
• Winner of Highly Commended in the Oncology Category, BMA Medical Book Awards 2011.

Overview

Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay of endocrine therapy in this group of patients, though anti-androgens, oestrogens and corticosteroids can also cause remissions. In recent years effective and well-tolerated chemotherapy regimens have been developed and evaluated. Docetaxel has an established role, and a range of biologically-targeted agents are in development. The dominant pattern of metastatic spread is to the axial skeleton and most symptomatic care is directed to palliation of bone pain. The role of bisphosphonates remains controversial, but bone-directed isotopes such as Strontium-89 are effective. Part of the Oxford Oncology Library, this pocketbook summarises the up-to-date information on the use of systemic therapies in the management of prostate cancer (early stage, metastatic disease, and treatment of ""biochemical"" recurrence). With contributions from leading oncologists from both Europe and the USA, the book provides a practical guide to the range of endocrine and cytotoxic therapies currently available to clinicians, as well as to other palliative anticancer strategies, and will be valuable to all health professionals involved in the management of patients with prostate cancer.

Full Product Details

Author:   Alan Horwich (Professor of Oncology, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 10.00cm , Height: 0.50cm , Length: 18.00cm
Weight:   0.093kg
ISBN:  

9780199561421

ISBN 10:   0199561427
Pages:   104
Publication Date:   11 February 2010
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Stock Indefinitely
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

1: Jonathan Waxman: Biological principles of hormone therapy 2: Karim Fizazi: PSA as a marker of progression and response 3: Mike D. Shelley and Malcolm D. Mason: Neoadjuvant and adjuvant hormone therapy for high-risk localized disease 4: Stephen Freedland: Systemic treatment of recurrence after local therapies 5: Ajjai S. Alva and Maha Hussain: First-line hormone therapy for metastatic prostate cancer 6: Wolfgang Lilleby and Sophie Fossa: Second- and third-line hormone therapies 7: Cora N. Sternberg and Fabio Calabro: Chemotherapy for metastatic prostate cancer 8: Alan Horwich and David P. Dearnley: The role of bisphosphonates in prostate cancer 9: Christopher C. Parker: Systemic isotope therapy of bone metastasis 10: Shahneen Sandhu and Johann DeBono: The development of biologically targeted agents

Reviews

Author Information

Alan Horwich is Professor of Oncology at the Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK.

Tab Content 6

Author Website:  

Countries Available

All regions