Overview

This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.

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9781441938770

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From the reviews: Brito-Arias ! provides an overview of the structures and synthetic preparations of O-, N-, and C-glycosides, as well as discussion of the conformational features and biological function of selected examples. ! The organization of the book provides a ready resource for researchers seeking information. Indeed, the references to published synthetic methodology or analytical data included at the end of each chapter will be useful for researchers seeking additional information or details on a specific topic. ! Summing Up: Recommended. Graduate students through professionals. (P. W. Baures, CHOICE, Vol. 44 (11), July, 2007)

From the reviews: Brito-Arias ... provides an overview of the structures and synthetic preparations of O-, N-, and C-glycosides, as well as discussion of the conformational features and biological function of selected examples. ... The organization of the book provides a ready resource for researchers seeking information. Indeed, the references to published synthetic methodology or analytical data included at the end of each chapter will be useful for researchers seeking additional information or details on a specific topic. ... Summing Up: Recommended. Graduate students through professionals. (P. W. Baures, CHOICE, Vol. 44 (11), July, 2007)

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