Overview

This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film’s extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials’ biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies. In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson’s disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders.  ​

Full Product Details

Author:   Je Min Yoo
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2020
Weight:   0.454kg
ISBN:  

9789811522321

ISBN 10:   9811522324
Pages:   68
Publication Date:   09 January 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Table of Contents Abstract of Dissertation............................................................................................................ i Table of Contents.................................................................................................................... iv List of Figures and Tables....................................................................................................... vi   Chapter 1. Introduction of Graphene-based Nanomaterials 1.1. Applications in Biology and Medical Science.................................................................. 1 1.1.1. Sensing Applications...................................................................................................... 2 1.1.2. Therapeutic Applications............................................................................................... 3 1.1.3. Fluorescence Bio-imaging............................................................................................. 4 1.2. Preparation of Graphene-based Nanomaterials................................................................ 6 1.2.1. Enhancing the Stability under Physiological Conditions.............................................. 7 1.2.2. Reduction of GOs........................................................................................................... 8 1.3. Toxicity of Graphene-based Nanomaterials..................................................................... 9 1.3.1. In vitro Toxicity of Graphene-based Nanomaterials..................................................... 9 1.3.2. In vivo Toxicity of Graphene-based Nanomaterials.................................................... 11 1.3.3. Biodegradation of Graphene-based Nanomaterials..................................................... 13 1.4. Perspectives and Other Applications.............................................................................. 15 1.5. References....................................................................................................................... 17   Chapter 2. Catalytic Degradation of Phenols by Recyclable CVD Grapehene Films 1.1. Abstract............................................................................................................................ 21 1.2. Introduction..................................................................................................................... 22 1.3. Results and Discussion.................................................................................................... 23 1.4. Conclusion....................................................................................................................... 31 1.5. Experimental................................................................................................................... 32 1.6. Supplementary Information............................................................................................ 34 1.7. References....................................................................................................................... 37   Chapter 3. Graphene Quantum Dots Prevent α-synucleinopathy in Parkinson’s Disease 1.1. Abstract............................................................................................................................ 39 1.2. Results and Discussion.................................................................................................... 40 1.3. Conclusion....................................................................................................................... 54 1.4. Experimental................................................................................................................... 54 1.5. Supplementary Information............................................................................................ 70 1.6. References....................................................................................................................... 89   Appendix............................................................................................................................... XX   Acknowledgements............................................................................................................... XX  

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Author Information

​Je Min Yoo earned a PhD degree in the Department of Chemistry, Seoul National University, Republic of Korea in 2019. His research interests focus on various biomedical application  of graphene technology.

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