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OverviewFull Product DetailsAuthor: Pandi VeerapandianPublisher: Taylor & Francis Inc Imprint: Routledge Dimensions: Width: 15.60cm , Height: 4.10cm , Length: 23.40cm Weight: 1.390kg ISBN: 9780824798697ISBN 10: 0824798694 Pages: 664 Publication Date: 08 July 1997 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsAIDS Inhibitors of HIV-1 Protease, Krzysztof Appelt A Review of Structural Studies of HIV-1 Reverse Transcriptase and Implications for Drug Design, Jianping Ding, Kalyan Das, Prem N. S. Yadav, Yu Hsiou, Wanyi Zhang, Stephen H. Hughes, and Edward Arnold Retroviral Integrase: Structure as a Foundation for Drug Design, Alison B. Hickman and Fred Dyda Arthritis and Inflammation Bradykinin Receptor Antagonists, Donald J. Kyle Cancer Design of Purine Nucleoside Phosphorylase Inhibitors, Y. Sudhakara Babu, John A. Montgomery, Charles E. Bugg, W. Michael Carson, Sthanam V. L. Narayana, William J. Cook, Steven E. Ealick, Wayne C. Guida, Mark Erion, and John Secrist III Structural Implications in the Design of Matrix-Metalloproteinase Inhibitors, John C. Spurlino Structure - Function Relationships in Hydroxysteroid Dehydrogenases, Igor Tsigelny and Michael Baker Design of ATP Competitive Specific Inhibitors of Protein Kinases Using Template Modeling, Janusz M. Sowadski, Charles A. Ellis, Rolf Karlsson, and Madhusudan Diabetes Mellitis Structural Studies of Aldose Reductase Inhibition, David K. Wilson, J. Mark Petrash, and Florante A. Quiocho Heart Diseases Structure-Based Design of Thrombin Inhibitors, Patricia C. Weber and Michael Czarniecki Design of Antithrombotic Agents Directed at Factor Xa, William C. Ripka Polypeptide Modulators of Sodium Channel Function as a Basis for the Development of Novel Cardiac Stimulants, Raymond S. Norton Rational Design of Renin Inhibitors, V. Dhanaraj and J. B. Cooper Parkinson's Disease Structural Aspects in the Inhibitor Design of Catechol O-Methyltransferase, Jukka Vidgren and Martti Ovaska Sleeping Sickness Antitrypanosomiasis Drug Development Based on Structures of Glycolytic Enzymes, Christopher L. M. J. Verlinde, Hidong Kim, Bradley E. Bernstein, Shekhar C. Mande, and Wim G. J. Hol Immune Diseases and Cytokines Progress in the Design of Immunomodulators Based on the Structure of Interleukin-1, Glen Spraggon and Pandi Veerapandian Structure and Functional Studies of Interferon: A Solid Foundation for Rational Drug Design, Michael A. Jarpe, Carol H. Pontzer, Brian E. Szente, and Howard M. Johnson Antivirals The Design of Anti-Influenza Virus Drugs from the X-Ray Molecular Structure of Influenza Virus Neuraminidase, Joseph N. Varghese Rhinoviral Capsid-Binding Inhibitors: Structural Basis for Understanding Rhinoviral Biology and for Drug Design, Vincent L. Giranda and Guy D. Diana Novel Methodologies The Integration of Structure-Based Design and Directed Combinatorial Chemistry for New Pharmaceutical Discovery, Roger Bone and F. Raymond Salemme Structure-Based Combinatorial Ligand Design, Amedeo Caflisch and Claus Ehrhardt Peptidomimetic and Neopeptide Drug Discovery: Impact on Structure-Based Drug Design, Tomi K. SawyerReviewsthe book is well-planned and executed, succeeding in giving the reader a fairly broad and complete overview of the many facets of structure based drug design. """ …Structure-Based Drug Design is an outstanding source of knowledge, inspiration, and delight. It is also a resonant proof that drug researchers are particularly fortunate scientists, being able to both uncover and contemplate the boundless complexities of Nature, and to actualize their awe by contributing to general health and well-being. ""-Journal of Pharmaceutical Research ""…the book is well-planned and executed, succeeding in giving the reader a fairly broad and complete overview of the many facets of structure based drug design. ""-Journal of Medicinal Chemistry" Author InformationPandi Veerapandian Tab Content 6Author Website:Countries AvailableAll regions |