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Author:   Mauricio G. Mateu
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 2013
Volume:   68
Weight:   1.512kg
ISBN:  

9789402401769

ISBN 10:   9402401768
Pages:   728
Publication Date:   27 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction: the structural basis of virus function.- The basic architecture of viruses.- Conventional electron microscopy, cryo-electron microscopy and cryo-electron tomography of viruses.- X-ray crystallography of viruses.- Nuclear magnetic resonance spectroscopy to study virus structure.- Fluorescence, circular dichroism and mass spectrometry as tools to study virus structure.- Combined approaches to study virus structure.- Atomic force microscopy of viruses.- Optical tweezers to study viruses.- Assembly of simple icosahedral viruses.- Structure and assembly of complex viruses.- Nucleic acid packaging in viruses.- Virus maturation.- Virus morphogenesis in the cell: methods and observations.- Virus-receptor interactions and receptor-mediated virus entry into host cells.- Entry of enveloped viruses into host cells: membrane fusion.- Bacteriophage receptor recognition and nucleic acid transfer.- Mechanical properties of viruses.- Theoretical studies on assembly, physical stabilityand dynamics of viruses.- Antiviral agents: Structural basis of action and rational design.- Design of novel vaccines based on virus-like particles or chimeric virions.- Nanoscale science and technology with plant viruses and bacteriophages.

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