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OverviewThis is a handbook for researchers and professional ecotoxicologists working on problems where there is sparse information on environmental toxins. It explains predictive mechanisms for obtaining information on likely outcomes based on the chemical structure of the compounds involved. Since Structure-Activity Relationships can be used as a predictive means to obtain information on chemicals if these are not available from experiments, these data can then be used for environmental fate and effects predictions and eventually for risk assessments. The multidisciplinary approach combines chemistry, biology, ecology, statistics and further related sciences, providing the reader with a theoretical basis as well as practical applications. This book should be of interest to environmental chemists, ecotoxicologists, environmental health workers, environmental risk assessors, chemists, and ecologists. Full Product DetailsAuthor: M. NendzaPublisher: Chapman and Hall Imprint: Chapman and Hall Edition: 1998 ed. Volume: 6 Dimensions: Width: 15.50cm , Height: 1.70cm , Length: 23.50cm Weight: 1.280kg ISBN: 9780412564307ISBN 10: 0412564300 Pages: 269 Publication Date: 31 December 1997 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsOne Theoretical Background.- 1 Descriptors of the chemical structures.- 2 Activity and effects parameters.- 3 Statistical methods.- Two Application of QSARs in Environmental Sciences.- 4 Exposure-related parameters.- 5 Effects-related parameters.- 6 Validation status of QSAR models for exposure-and effects-related parameters.- Three Application of QSARs in Environmental Hazard and Risk Assessments.- 7 Assessments of chemical mixtures.- 8 Interspecies correlations.- 9 Application of QSAR estimates in hazard evaluation and risk assessment.- Appendix: QSAR-related computer programs and software.- References and bibliography.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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