Structure—Activity Relationships in Environmental Sciences

Author:   M. Nendza
Publisher:   Chapman and Hall
Edition:   1998 ed.
Volume:   6
ISBN:  

9780412564307


Pages:   269
Publication Date:   31 December 1997
Format:   Hardback
Availability:   In Print   Availability explained
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Structure—Activity Relationships in Environmental Sciences


Overview

This is a handbook for researchers and professional ecotoxicologists working on problems where there is sparse information on environmental toxins. It explains predictive mechanisms for obtaining information on likely outcomes based on the chemical structure of the compounds involved. Since Structure-Activity Relationships can be used as a predictive means to obtain information on chemicals if these are not available from experiments, these data can then be used for environmental fate and effects predictions and eventually for risk assessments. The multidisciplinary approach combines chemistry, biology, ecology, statistics and further related sciences, providing the reader with a theoretical basis as well as practical applications. This book should be of interest to environmental chemists, ecotoxicologists, environmental health workers, environmental risk assessors, chemists, and ecologists.

Full Product Details

Author:   M. Nendza
Publisher:   Chapman and Hall
Imprint:   Chapman and Hall
Edition:   1998 ed.
Volume:   6
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   1.280kg
ISBN:  

9780412564307


ISBN 10:   0412564300
Pages:   269
Publication Date:   31 December 1997
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

One Theoretical Background.- 1 Descriptors of the chemical structures.- 2 Activity and effects parameters.- 3 Statistical methods.- Two Application of QSARs in Environmental Sciences.- 4 Exposure-related parameters.- 5 Effects-related parameters.- 6 Validation status of QSAR models for exposure-and effects-related parameters.- Three Application of QSARs in Environmental Hazard and Risk Assessments.- 7 Assessments of chemical mixtures.- 8 Interspecies correlations.- 9 Application of QSAR estimates in hazard evaluation and risk assessment.- Appendix: QSAR-related computer programs and software.- References and bibliography.

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