Neurosteroid Effects in the Central Nervous System: The Role of the GABA-A Receptor

Author:   Sheryl S. Smith ,  Sidney A. Simon ,  Miguel A. L. Nicolelis ,  Richard W. Olsen
Publisher:   Taylor & Francis Inc
ISBN:  

9780849323928


Pages:   406
Publication Date:   27 October 2003
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Neurosteroid Effects in the Central Nervous System: The Role of the GABA-A Receptor


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Full Product Details

Author:   Sheryl S. Smith ,  Sidney A. Simon ,  Miguel A. L. Nicolelis ,  Richard W. Olsen
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Dimensions:   Width: 15.60cm , Height: 2.50cm , Length: 23.40cm
Weight:   0.743kg
ISBN:  

9780849323928


ISBN 10:   0849323924
Pages:   406
Publication Date:   27 October 2003
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction. Synthesis, enzyme localization, and regulation of neurosteroids. Subunit specificity of steroid modulation of GABAA receptors. THDOC and the GABAA receptor. Neurosteoid modulation of delta subunit-containing GABA-A receptor channels. Potentiation and inhibition of GABAA receptor function by neuroactive steroids. Anabolic androgenic steroids and the brain: Novel actions at the GABAA receptor and on GABA-A receptor mediated behaviors. Withdrawal effects of a neuroactive steroid as a model of PMS: Synaptic physiology to behavior. GABA, estrogen, and sex differences in the brain. FGIN-1-X--A series of novel specific and efficacious ligands for the peripheral benzodiazepine receptor. GABAergic neuroactive steroids modulate selective ethanol actions: Mechanisms and significance. Allopregnanolone modulates the action of ethanol and stress on the activity of mesocortical dopaminergic neurons and HPA axis. 3a, 5a-THP's actions in the ventral tegmental area for lordosis: A model system for defining mechanisms and function of progestins. Premenstrual dysphoric disorder. Role of neurosteroids in epilepsy. Animal models of anxiety and stress-induced behavior: Effects of neuroactive steroids. Direct modulation of amino acid receptors by neuroactive steroids: Physiological and pharmacological Implications. On the neurosteroid mechanisms of action and their clinical potentials.

Reviews

The overwhelming amount of information in the field is well presented in the superbly written book, the magnificent pictures, and the up-to-date references. This is a good purchase for general neurological and neuroscience libraries. - Doody's Promo Copy


The overwhelming amount of information in the field is well presented in the superbly written book, the magnificent pictures, and the up-to-date references. This is a good purchase for general neurological and neuroscience libraries. - Doody's Promo Copy


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Smith\, Sheryl S.

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