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OverviewRecent evidence demonstrates that normal prostate tissue contains stem cells. There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells. Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer. The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research. Full Product DetailsAuthor: Scott D. CramerPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2013 ed. Dimensions: Width: 15.50cm , Height: 1.00cm , Length: 23.50cm Weight: 2.993kg ISBN: 9781493900947ISBN 10: 1493900943 Pages: 182 Publication Date: 08 February 2015 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface.- Stem Cells and Prostate Development.- Isolation and Characterization of Prostate Stem Cells.- Prostate tumor initiating cells.- TIC Markers and methods of characterization.- Genetic Control of Self Renewal of the TIC.- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes.- Index .ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |