Overview

The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents the latest research from around the globe in this dynamic field.

Full Product Details

Author:   Dr Prasad S Koka
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 18.30cm , Height: 2.00cm , Length: 25.90cm
Weight:   0.752kg
ISBN:  

9781604563085

ISBN 10:   1604563087
Pages:   194
Publication Date:   01 June 2008
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Unknown
Availability:   Out of stock  

Table of Contents

Preface; Functional Significance of Active Dye Exclusion by Human Hematopoietic Progenitors After Short-Term Culture; The Effects of Ex Vivo Expansion on the Rheology of Umbilical Cord Blood-Derived CD34+ Cells; Comparison of the Differentiation Potential of Cell Populations Isolated From Human Lipoaspirate, Trabecular Bone Tissue and Periosteal Tissue; Adult Neural Stem Cells and Their Niches: Developmental and Therapeutic Implications; An Analysis of the Arguments Underpinning UK Embryonic Stem Cell Legislation on the Embryo's Status; A Tetracycline-Inducible Lentivector System Based on EF1-Alpha Promoter and Native Tetracycline Repressor Allows in Vivo Gene Induction in Implanted ES Cells 7. Bone Marrow and Adipose Tissue-Derived Mesenchymal Stem Cells: How Close Are They; From The Bone Marrow to the Periphery: The Ontogeny and Function of Dendritic Cell Populations; Advances Towards the Development of a Stem Cell Therapy for Hirschsprung's Disease; The Role of Stem Cells in Repair of Acute Lung Injury; Index.

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