Overview

Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells before delving into the interaction across various conditions, ranging from cerebral injury, spinal injury, cardiac injury, osteoarthritis, cancer, and more. Users will find the latest research and future directions in the study of stem cells and pyroptosis, thus enabling further understanding of the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. Therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions are also considered, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics, and other related fields.

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9780443404719

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Debalina Bhattacharya is currently working as an Assistant Professor in the Department of Microbiology, Maulana Azad College, West Bengal, India. Previously, she worked as a postdoctoral fellow in the Department of Biotechnology and Department of Biochemistry, University of Calcutta, West Bengal, India. She holds a PhD in bionanotechnology from Jadavpur University, West Bengal, India. She has been awarded UGC DS Kothari Post-Doctoral Fellowship in 2015 and DST-SERB National Post-Doctoral fellowship in 2018. She has co-authored 24 peer-reviewed research articles and review articles and 17 book chapters. She has also previously co-edited a book with Elsevier, ""Exosomal RNA: Role in Human Diseases and Therapy"". Dr. Mainak Mukhopadhyay is currently working as Associate Professor at the Department of Biosciences, JIS University, Kolkata, India. Previously, he worked as a research fellow at ONGC Energy Centre, Delhi, India. He holds a PhD in Bioenergy from the Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, India. He has been awarded the Petrotech Research Fellowship in 2008. In 2016 he was awarded the Early Career Research Award from DST-SERB. In addition to editing two books, he has co-authored 13 peer-reviewed papers, 19 book chapters and filled 3 patents. He has also co-edited another book with Elsevier, ""Exosomal RNA: Role in Human Diseases and Therapy"".

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