Statistical Methods in Molecular Biology

Author:   Heejung Bang ,  Xi Kathy Zhou ,  Heather L. van Epps ,  Madhu Mazumdar
Publisher:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 2010
Volume:   620
ISBN:  

9781493961245


Pages:   636
Publication Date:   23 August 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Statistical Methods in Molecular Biology


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Overview

Part I: Basic Statistics 1. Experimental Statistics for Biological Sciences Heejung Bang and Marie Davidian 2. Nonparametric Methods in Molecular Biology Knut M. Wittkowski and Tingting Song 3. Basics of Bayesian Methods Sujit K. Ghosh 4. The Bayesian t-Test and Beyond Mithat Gönen Part II: Designs and Methods for Molecular Biology 5. Sample Size and Power Calculation for Molecular Biology Studies Sin-Ho Jung 6. Designs for Linkage Analysis and Association Studies of Complex Diseases Yuehua Cui, Gengxin Li, Shaoyu Li, and Rongling Wu 7. Introduction to Epigenomics and Epigenome-Wide Analysis Melissa J. Fazzari and John M. Greally 8. Exploration, Visualization, and Preprocessing of High Dimensional Data Zhijin Wu and Zhiqiang Wu Part III: Statistical Methods for Microarray Data 9. Introduction to the Statistical Analysis of Two-Color Microarray Data Martina Bremer, Edward Himelblau, and Andreas Madlung 10. Building Networks with Microarray Data Bradley M. Broom, Waree Rinsurongkawong, Lajos Pusztai, and Kim-Anh Do Part IV: Advanced or Specialized Methods for Molecular Biology 11. Support Vector Machines for Classification: A Statistical Portrait Yoonkyung Lee 12. An Overview of Clustering Applied to Molecular Biology Rebecca Nugent and Marina Meila 13. Hidden Markov Model and Its Applications in Motif Findings Jing Wu and Jun Xie 14. Dimension Reduction for High Dimensional Data Lexin Li 15. Introduction to the Development and Validation of Predictive Biomarker Models from High-Throughput Datasets Xutao Deng and Fabien Campagne 16. Multi-GeneExpression-Based Statistical Approaches to Predicting Patients' Clinical Outcomes and Responses Feng Cheng, Sang-Hoon Cho, and Jae K. Lee 17. Two-Stage Testing Strategies for Genome-Wide Association Studies in Family-Based Designs Amy Murphy, Scott T. Weiss, and Christoph Lange 18. Statistical Methods for Proteomics Klaus Jung Part V: Meta-Analysis for High-Dimensional Data 19. Statistical Methods for Integrating Multiple Types of High-Throughput Data Yang Xie and Chul Ahn 20. A Bayesian Hierarchical Model for High-Dimensional Meta Analysis Fei Liu 21. Methods for Combining Multiple Genome-Wide Linkage Studies Trecia A. Kippola and Stephanie A. Santorico Part VI: Other Practical Information 22. Improved Reporting of Statistical Design and Analysis: Guidelines, Education, and Editorial Policies Madhu Mazumdar, Samprit Banerjee, and Heather L. Van Epps 23. Stata Companion Jennifer Sousa Brennan

Full Product Details

Author:   Heejung Bang ,  Xi Kathy Zhou ,  Heather L. van Epps ,  Madhu Mazumdar
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 2010
Volume:   620
Weight:   1.222kg
ISBN:  

9781493961245


ISBN 10:   1493961241
Pages:   636
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Basic Statistics.- Experimental Statistics for Biological Sciences.- Nonparametric Methods for Molecular Biology.- Basics of Bayesian Methods.- The Bayesian t-Test and Beyond.- Designs and Methods for Molecular Biology.- Sample Size and Power Calculation for Molecular Biology Studies.- Designs for Linkage Analysis and Association Studies of Complex Diseases.- to Epigenomics and Epigenome-Wide Analysis.- Exploration, Visualization, and Preprocessing of High–Dimensional Data.- Statistical Methods for Microarray Data.- to the Statistical Analysis of Two-Color Microarray Data.- Building Networks with Microarray Data.- Advanced or Specialized Methods for Molecular Biology.- Support Vector Machines for Classification: A Statistical Portrait.- An Overview of Clustering Applied to Molecular Biology.- Hidden Markov Model and Its Applications in Motif Findings.- Dimension Reduction for High-Dimensional Data.- to the Development and Validation of Predictive Biomarker Models from High-Throughput Data Sets.- Multi-gene Expression-based Statistical Approaches to Predicting Patients’ Clinical Outcomes and Responses.- Two-Stage Testing Strategies for Genome-Wide Association Studies in Family-Based Designs.- Statistical Methods for Proteomics.- Meta-Analysis for High-Dimensional Data.- Statistical Methods for Integrating Multiple Types of High-Throughput Data.- A Bayesian Hierarchical Model for High-Dimensional Meta-analysis.- Methods for Combining Multiple Genome-Wide Linkage Studies.- Other Practical Information.- Improved Reporting of Statistical Design and Analysis: Guidelines, Education, and Editorial Policies.- Stata Companion.

Reviews

"""Here is a comprehensive book that systematically covers both basic and advanced statistical topics in molecular biology, including parametric and nonparametric, and frequentist and Bayesian methods. I am highly impressed by the breadth and depth of the applications. I strongly recommend this book for both statisticians and biologists who need to communicate with each other in this exciting field of research."" (Robert C. Elston, PhD., Director, Division of Genetic and Molecular Epidemiology, Case Western Reserve University) ""An extraordinary exposition of the central topics of modern molecular biology, presented by practicing experts who weave together rigorous theory with practical techniques and illustrative examples."" (George C. Newman, MD, PhD, Chairman, Neurosensory Sciences, Albert Einstein Medical Center) ""I cannot think of anything we need now in translation research field more than more efficient cross talk between molecular biology and statistics. This book is just on target. It fills the gap."" (Iman Osman, MB, BCh, MD, Director, Interdisciplinary Melanoma Cooperative Program, New York University Langone Medical Center)"


Here is a comprehensive book that systematically covers both basic and advanced statistical topics in molecular biology, including parametric and nonparametric, and frequentist and Bayesian methods. I am highly impressed by the breadth and depth of the applications. I strongly recommend this book for both statisticians and biologists who need to communicate with each other in this exciting field of research. (Robert C. Elston, PhD., Director, Division of Genetic and Molecular Epidemiology, Case Western Reserve University) An extraordinary exposition of the central topics of modern molecular biology, presented by practicing experts who weave together rigorous theory with practical techniques and illustrative examples. (George C. Newman, MD, PhD, Chairman, Neurosensory Sciences, Albert Einstein Medical Center) I cannot think of anything we need now in translation research field more than more efficient cross talk between molecular biology and statistics. This book is just on target. It fills the gap. (Iman Osman, MB, BCh, MD, Director, Interdisciplinary Melanoma Cooperative Program, New York University Langone Medical Center)


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